PTPN11

DescriptionTyrosine-protein phosphatase non-receptor type 11

Gene and Protein Information

Gene ID5781
Uniprot Accession IDs Q06124 A8K1D9 Q96HD7
Ensembl ID ENSP00000340944
Symbol PTP2C SHPTP2 CFC NS1 JMML SHP2 BPTP3 PTP2C METCDS PTP-1D SH-PTP2 SH-PTP3
FamilyBelongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
Sequence
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp104001066PTPN11protein tyrosine phosphatase, non-receptor type 119598VGNC:5553OMA, EggNOG
Macaque712044PTPN11protein tyrosine phosphatase, non-receptor type 119544Inparanoid, OMA, EggNOG
Mouse19247Ptpn11protein tyrosine phosphatase, non-receptor type 1110090MGI:99511Inparanoid, OMA, EggNOG
Rat25622Ptpn11protein tyrosine phosphatase, non-receptor type 1110116RGD:3447Inparanoid, OMA, EggNOG
Dog477488PTPN11protein tyrosine phosphatase, non-receptor type 119615VGNC:45168Inparanoid, OMA, EggNOG
Horse100056857PTPN11protein tyrosine phosphatase, non-receptor type 119796VGNC:22011Inparanoid, OMA, EggNOG
Cow533590PTPN11protein tyrosine phosphatase, non-receptor type 119913VGNC:33530Inparanoid, OMA, EggNOG
Pig100170851PTPN11protein tyrosine phosphatase, non-receptor type 119823Inparanoid, OMA, EggNOG
Opossum100028991PTPN11protein tyrosine phosphatase, non-receptor type 1113616Inparanoid, OMA, EggNOG
Chicken395815PTPN11protein tyrosine phosphatase, non-receptor type 119031CGNC:49495Inparanoid, OMA
Anole lizard100559345ptpn11protein tyrosine phosphatase, non-receptor type 1128377Inparanoid, OMA
Zebrafish333979ptpn11aprotein tyrosine phosphatase, non-receptor type 11, a7955ZDB-GENE-030131-5911Inparanoid, OMA
Fruitfly45278cswcorkscrew7227FBgn0000382Inparanoid, OMA

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

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