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| Description | RAF proto-oncogene serine/threonine-protein kinase |
|---|
Gene and Protein Information
| Gene ID | 5894 |
|---|---|
| Uniprot Accession IDs | P04049 B0LPH8 B2R5N3 Q15278 Q9UC20 |
| Ensembl ID | ENSP00000251849 |
| Symbol | RAF NS5 CRAF Raf-1 c-Raf CMD1NN |
| Family | Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. |
| Sequence | MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 460182 | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase | 9598 | VGNC:12161 | OMA, EggNOG |
| Macaque | 694725 | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 110157 | Raf1 | v-raf-leukemia viral oncogene 1 | 10090 | MGI:97847 | Inparanoid, OMA, EggNOG |
| Rat | 24703 | Raf1 | Raf-1 proto-oncogene, serine/threonine kinase | 10116 | RGD:3531 | Inparanoid, OMA |
| Dog | 484648 | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase | 9615 | VGNC:45325 | Inparanoid, OMA |
| Horse | 100051110 | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase | 9796 | Inparanoid, OMA | |
| Opossum | 100015410 | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase | 13616 | Inparanoid, OMA | |
| Chicken | 396245 | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase | 9031 | CGNC:3714 | Inparanoid, OMA |
| Anole lizard | 100557613 | raf1 | Raf-1 proto-oncogene, serine/threonine kinase | 28377 | Inparanoid, OMA | |
| Zebrafish | 557109 | raf1b | Raf-1 proto-oncogene, serine/threonine kinase b | 7955 | ZDB-GENE-090826-2 | Inparanoid, OMA, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TKL group / RAF family / Raf proto-oncogene serine/threonine-protein kinase
protein / Kinase / Protein kinase / TKL group / RAF family / Raf proto-oncogene serine/threonine-protein kinase
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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