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| Description | Proto-oncogene tyrosine-protein kinase receptor Ret |
|---|
Gene and Protein Information
| Gene ID | 5979 |
|---|---|
| Uniprot Accession IDs | P07949 A8K6Z2 Q15250 Q9BTB0 Q9H4A2 |
| Ensembl ID | ENSP00000347942 |
| Symbol | CDHF12 CDHR16 PTC RET51 PTC MTC1 HSCR1 MEN2A MEN2B CDHF12 CDHR16 RET-ELE1 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. |
| Sequence | MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELVAVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRYPNDSVYANWMLSPSAAKLMDTFDS Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 100612888 | RET | ret proto-oncogene | 9598 | VGNC:12455 | OMA, EggNOG |
| Macaque | 703466 | RET | ret proto-oncogene | 9544 | OMA, EggNOG | |
| Mouse | 19713 | Ret | ret proto-oncogene | 10090 | MGI:97902 | Inparanoid, OMA, EggNOG |
| Rat | 24716 | Ret | ret proto-oncogene | 10116 | RGD:3556 | Inparanoid, OMA, EggNOG |
| Dog | 403494 | RET | ret proto-oncogene | 9615 | VGNC:45481 | Inparanoid, OMA, EggNOG |
| Horse | 100146791 | RET | ret proto-oncogene | 9796 | VGNC:51660 | OMA, EggNOG |
| Cow | 515924 | RET | ret proto-oncogene | 9913 | VGNC:33876 | Inparanoid, OMA, EggNOG |
| Pig | 100155053 | RET | ret proto-oncogene | 9823 | OMA, EggNOG | |
| Opossum | 100016023 | RET | ret proto-oncogene | 13616 | Inparanoid, EggNOG | |
| Chicken | 396107 | RET | ret proto-oncogene | 9031 | CGNC:1837 | Inparanoid, OMA |
| Anole lizard | RET | ret proto-oncogene [Source:HGNC Symbol;Acc:HGNC:9967] | 28377 | Inparanoid, OMA, EggNOG | ||
| Xenopus | 100495902 | ret | ret proto-oncogene | 8364 | XB-GENE-485176 | Inparanoid, OMA, EggNOG |
| Zebrafish | 30512 | ret | ret proto-oncogene receptor tyrosine kinase | 7955 | ZDB-GENE-980526-307 | Inparanoid, OMA, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / RET family / Proto-oncogene tyrosine-protein kinase receptor ret
protein / Kinase / Protein kinase / TK group / RET family / Proto-oncogene tyrosine-protein kinase receptor ret
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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