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PFAS

DescriptionPhosphoribosylformylglycinamidine synthase

Gene and Protein Information

Gene ID5198
Uniprot Accession IDs O15067 A6H8V8 FGAM synthase
Ensembl ID ENSP00000313490
Symbol KIAA0361 PURL FGAMS GATD8 FGARAT FGAR-AT
FamilyIn the N-terminal section; belongs to the FGAMS family.
Sequence
MSPVLHFYVRPSGHEGAAPGHTRRKLQGKLPELQGVETELCYNVNWTAEALPSAEETKKLMWLFGCPLLLDDVARESWLLPGSNDLLLEVGPRLNFSTPTSTNIVSVCRATGLGPVDRVETTRRYRLSFAHPPSAEVEAIALATLHDRMTEQHFPHPIQSFSPESMPEPLNGPINILGEGRLALEKANQELGLALDSWDLDFYTKRFQELQRNPSTVEAFDLAQSNSEHSRHWFFKGQLHVDGQKLVHSLFESIMSTQESSNPNNVLKFCDNSSAIQGKEVRFLRPEDPTRPSRFQQQQGLRHVVFTAETHNFPTGVCPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGYNLPWEDPSFQYPGNFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREWIKPIMFSGGIGSMEADHISKEAPEPGMEVVKVGGPVYRIGVGGGAASSVQVQGDNTSDLDFGAVQRGDPEMEQKMNRVIRACVEAPKGNPICSLHDQGAGGNGNVLKELSDPAGAIIYTSRFQLGDPTLNALEIWGAEYQESNALLLRSPNRDFLTHVSARERCPACFVGTITGDRRIVLVDDRECPVRRNGQGDAPPTPLPTPVDLELEWVLGKMPRKEFFLQRKPPMLQPLALPPGLSVHQALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHEELIGAATALGEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAALADACEAMVAVMAALGVAVDGGKDSLSMAARVGTETVRAPGSLVISAYAVCPDITATVTPDLKHPEGRGHLLYVALSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVRAFSITQGLLKDRLLCSGHDVSDGGLVTCLLEMAFAGNCGLQVDVPVPRVDVLSVLFAEEPGLVLEVQEPDLAQVLKRYRDAGLHCLELGHTGEAGPHAMVRVSVNGAVVLEEPVGELRALWEETSFQLDRLQAEPRCVAEEERGLRERMGPSYCLPPTFPKASVPREPGGPSPRVAILREEGSNGDREMADAFHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFHPRAGAELRRFRKRPDTFSLGVCNGCQLLALLGWVGGDPNEDAAEMGPDSQPARPGLLLRHNLSGRYESRWASVRVGPGPALMLRGMEGAVLPVWSAHGEGYVAFSSPELQAQIEARGLAPLHWADDDGNPTEQYPLNPNGSPGGVAGICSCDGRHLAVMPHPERAVRPWQWAWRPPPFDTLTTSPWLQLFINARNWTLEGSC
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp455093PFASphosphoribosylformylglycinamidine synthase9598VGNC:9510OMA, EggNOG
Macaque717046PFASphosphoribosylformylglycinamidine synthase9544Inparanoid, OMA, EggNOG
Mouse237823Pfasphosphoribosylformylglycinamidine synthase (FGAR amidotransferase)10090MGI:2684864Inparanoid, OMA, EggNOG
Rat287420Pfasphosphoribosylformylglycinamidine synthase10116RGD:1304926Inparanoid, OMA, EggNOG
Dog489490PFASphosphoribosylformylglycinamidine synthase9615VGNC:44439Inparanoid, OMA, EggNOG
Horse100062488PFASphosphoribosylformylglycinamidine synthase9796VGNC:21332Inparanoid, OMA, EggNOG
Cow520318PFASphosphoribosylformylglycinamidine synthase9913VGNC:32765Inparanoid, OMA, EggNOG
Pig100620093PFASphosphoribosylformylglycinamidine synthase9823Inparanoid, OMA, EggNOG
Opossum100013885PFASphosphoribosylformylglycinamidine synthase13616Inparanoid, OMA, EggNOG
Anole lizard100559217pfasphosphoribosylformylglycinamidine synthase28377Inparanoid, OMA, EggNOG
XenopusPFASphosphoribosylformylglycinamidine synthase [Source:HGNC Symbol;Acc:HGNC:8863]8364OMA, EggNOG
Zebrafish570437pfasphosphoribosylformylglycinamidine synthase7955ZDB-GENE-030131-4420Inparanoid, OMA, EggNOG
C. elegans175608F10F2.2Probable phosphoribosylformylglycinamidine synthase6239Inparanoid, OMA, EggNOG
Fruitfly33847ade2adenosine 27227FBgn0000052Inparanoid, OMA, EggNOG
S.cerevisiae852952ADE6phosphoribosylformylglycinamidine synthase4932S000003293Inparanoid, OMA, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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