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PRKN

DescriptionE3 ubiquitin-protein ligase parkin

Gene and Protein Information

Gene ID5071
Uniprot Accession IDs O60260 A3FG77 A8K975 D3JZW7 D3K2X0 Q5TFV8 Q5VVX4 Q6Q2I6 Q8NI41 Q8NI43 Q8NI44 Q8WW07 Parkin
Ensembl ID ENSP00000355865
Symbol PARK2 PDJ AR-JP LPRS2 PARK2
FamilyBelongs to the RBR family. Parkin subfamily.
Sequence
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp741350PRKNparkin RBR E3 ubiquitin protein ligase9598VGNC:13029OMA, EggNOG
Macaque710899PRKNparkin RBR E3 ubiquitin protein ligase9544OMA, EggNOG
Mouse50873Park2Parkinson disease (autosomal recessive, juvenile) 2, parkin10090MGI:1355296Inparanoid, OMA
HorsePRKNparkin RBR E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:8607]9796OMA, EggNOG
Cow530858PRKNparkin RBR E3 ubiquitin protein ligase9913VGNC:33342OMA, EggNOG
Chicken421577PARK2parkin RBR E3 ubiquitin protein ligase9031CGNC:8787Inparanoid, OMA, EggNOG
Zebrafish550328prknparkin RBR E3 ubiquitin protein ligase7955ZDB-GENE-050417-109OMA, EggNOG
C. elegans176816pdr-1E3 ubiquitin-protein ligase parkin6239Inparanoid, OMA
Fruitfly40336parkparkin7227FBgn0041100Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    ligase    /    ubiquitin-protein ligase    /    E3 ubiquitin-protein ligase parkin
DTO Classes
protein    /    Enzyme    /    Ligase    /    Ubiquitin-protein ligase    /    E3 ubiquitin-protein ligase parkin

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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