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SCNN1A

DescriptionAmiloride-sensitive sodium channel subunit alpha

Gene and Protein Information

Gene ID6337
Uniprot Accession IDs P37088 A5X2U9 B4E2Q5 C5HTZ0 O43271 Q6GSQ6 Q9UM64
Ensembl ID ENSP00000353292
Symbol SCNN1 BESC2 ENaCa SCNEA SCNN1 LIDLS3 ENaCalpha
FamilyBelongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1A subfamily.
Sequence
MEGNKLEEQDSSPPQSTPGLMKGNKREEQGLGPEPAAPQQPTAEEEALIEFHRSYRELFEFFCNNTTIHGAIRLVCSQHNRMKTAFWAVLWLCTFGMMYWQFGLLFGEYFSYPVSLNINLNSDKLVFPAVTICTLNPYRYPEIKEELEELDRITEQTLFDLYKYSSFTTLVAGSRSRRDLRGTLPHPLQRLRVPPPPHGARRARSVASSLRDNNPQVDWKDWKIGFQLCNQNKSDCFYQTYSSGVDAVREWYRFHYINILSRLPETLPSLEEDTLGNFIFACRFNQVSCNQANYSHFHHPMYGNCYTFNDKNNSNLWMSSMPGINNGLSLMLRAEQNDFIPLLSTVTGARVMVHGQDEPAFMDDGGFNLRPGVETSISMRKETLDRLGGDYGDCTKNGSDVPVENLYPSKYTQQVCIHSCFQESMIKECGCAYIFYPRPQNVEYCDYRKHSSWGYCYYKLQVDFSSDHLGCFTKCRKPCSVTSYQLSAGYSRWPSVTSQEWVFQMLSRQNNYTVNNKRNGVAKVNIFFKELNYKTNSESPSVTMVTLLSNLGSQWSLWFGSSVLSVVEMAELVFDLLVIMFLMLLRRFRSRYWSPGRGGRGAQEVASTLASSPPSHFCPHPMSLSLSQPGPAPSPALTAPPPAYATLGPRPSPGGSAGASSSTCPLGGP
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp451776SCNN1Asodium channel epithelial 1 alpha subunit9598VGNC:13442Inparanoid, OMA, EggNOG
Macaque712476SCNN1Asodium channel epithelial 1 alpha subunit9544Inparanoid, OMA, EggNOG
Mouse20276Scnn1asodium channel, nonvoltage-gated 1 alpha10090MGI:101782Inparanoid, OMA, EggNOG
Rat25122Scnn1asodium channel epithelial 1 alpha subunit10116RGD:3639Inparanoid, OMA, EggNOG
Dog403650SCNN1Asodium channel epithelial 1 alpha subunit9615VGNC:45925Inparanoid, OMA, EggNOG
Horse100059623SCNN1Asodium channel epithelial 1 alpha subunit9796VGNC:22744Inparanoid, OMA, EggNOG
Cow282348SCNN1Asodium channel epithelial 1 alpha subunit9913VGNC:49961Inparanoid, OMA, EggNOG
Pig396608SCNN1Asodium channel epithelial 1 alpha subunit9823Inparanoid, OMA, EggNOG
Opossum100014763SCNN1Asodium channel epithelial 1 alpha subunit13616Inparanoid, OMA, EggNOG
PlatypusSCNN1Asodium channel epithelial 1 alpha subunit [Source:HGNC Symbol;Acc:HGNC:10599]9258OMA, EggNOG
Anole lizard100565527scnn1asodium channel epithelial 1 alpha subunit28377Inparanoid, OMA, EggNOG
Xenopus395013scnn1asodium channel, non voltage gated 1 alpha subunit8364XB-GENE-996083Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    ion channel    /    Amiloride-sensitive sodium channel subunit alpha
DTO Classes
protein    /    Ion channel    /    Amiloride-sensitive sodium channel family    /    SCNN1A subfamily    /    Amiloride-sensitive sodium channel subunit alpha

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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