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| Description | Sodium channel protein type 2 subunit alpha |
|---|
Gene and Protein Information
| Gene ID | 6326 |
|---|---|
| Uniprot Accession IDs | Q99250 A6NC14 A6NIQ5 Q14472 Q53T77 Q9BZC9 Q9BZD0 |
| Ensembl ID | ENSP00000364586 |
| Symbol | NAC2 SCN2A1 SCN2A2 HBA NAC2 BFIC3 BFIS3 BFNIS HBSCI EIEE11 HBSCII Nav1.2 SCN2A1 SCN2A2 Na(v)1.2 |
| Family | Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.2/SCN2A subfamily. |
| Sequence | MAQSVLVPPGPDSFRFFTRESLAAIEQRIAEEKAKRPKQERKDEDDENGPKPNSDLEAGKSLPFIYGDIPPEMVSVPLEDLDPYYINKKTFIVLNKGKAISRFSATPALYILTPFNPIRKLAIKILVHSLFNMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPDNSSFEINITSFFNNSLDGNGTTFNRTVSIFNWDEYIEDKSHFYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEEAQAAAAAASAESRDFSGAGGIGVFSESSSVASKLSSKSEKELKNRRKKKKQKEQSGEEEKNDRVRKSESEDSIRRKGFRFSLEGSRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRASLFSFRGRAKDIGSENDFADDEHSTFEDNDSRRDSLFVPHRHGERRHSNVSQASRASRVLPILPMNGKMHSAVDCNGVVSLVGGPSTLTSAGQLLPEGTTTETEIRKRRSSSYHVSMDLLEDPTSRQRAMSIASILTNTMEELEESRQKCPPCWYKFANMCLIWDCCKPWLKVKHLVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSSVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISNDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRMQKGIDFVKRKIREFIQKAFVRKQKALDEIKPLEDLNNKKDSCISNHTTIEIGKDLNYLKDGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESDMEESKEKLNATSSSEGSTVDIGAPAEGEQPEVEPEESLEPEACFTEDCVRKFKCCQISIEEGKGKLWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQVYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINYTTGEMFDVSVVNNYSECKALIESNQTARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQVFDISIMILICLNMVTMMVETDDQSQEMTNILYWINLVFIVLFTGECVLKLISLRYYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGPPDCDPDKDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFAKLSDFADALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYEPITTTLKRKQEEVSAIIIQRAYRRYLLKQKVKKVSSIYKKDKGKECDGTPIKEDTLIDKLNENSTPEKTDMTPSTTSPPSYDSVTKPEKEKFEKDKSEKEDKGKDIRESKK Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 459700 | SCN2A | sodium voltage-gated channel alpha subunit 2 | 9598 | VGNC:14354 | OMA, EggNOG |
| Macaque | 703298 | SCN2A | sodium voltage-gated channel alpha subunit 2 | 9544 | Inparanoid, OMA | |
| Mouse | 110876 | Scn2a | sodium channel, voltage-gated, type II, alpha | 10090 | MGI:98248 | OMA, EggNOG |
| Rat | 24766 | Scn2a | sodium voltage-gated channel alpha subunit 2 | 10116 | RGD:3632 | Inparanoid, OMA |
| Dog | 478773 | SCN2A | sodium voltage-gated channel alpha subunit 2 | 9615 | VGNC:53105 | Inparanoid, OMA |
| Horse | 100051816 | SCN2A | sodium voltage-gated channel alpha subunit 2 | 9796 | VGNC:22734 | Inparanoid, OMA |
| Cow | 539718 | SCN2A | sodium voltage-gated channel alpha subunit 2 | 9913 | VGNC:34347 | Inparanoid, OMA |
| Pig | 100515171 | LOC100515171 | sodium channel protein type 2 subunit alpha | 9823 | Inparanoid, OMA | |
| Opossum | 100016409 | SCN2A | sodium voltage-gated channel alpha subunit 2 | 13616 | Inparanoid, OMA | |
| Chicken | 395945 | SCN2A | sodium voltage-gated channel alpha subunit 2 | 9031 | CGNC:49566 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / transporter / calcium channel / Sodium channel protein type 2 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 2 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 2 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 2 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 2 subunit alpha
protein / transporter / calcium channel / Sodium channel protein type 2 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 2 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 2 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 2 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 2 subunit alpha
DTO Classes
protein / Ion channel / Sodium channel family / Nav1.2/SCN2A subfamily / Sodium channel protein type 2 subunit alpha
protein / Ion channel / Sodium channel family / Nav1.2/SCN2A subfamily / Sodium channel protein type 2 subunit alpha
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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