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SCN2A

DescriptionSodium channel protein type 2 subunit alpha

Gene and Protein Information

Gene ID6326
Uniprot Accession IDs Q99250 A6NC14 A6NIQ5 Q14472 Q53T77 Q9BZC9 Q9BZD0
Ensembl ID ENSP00000364586
Symbol NAC2 SCN2A1 SCN2A2 HBA NAC2 BFIC3 BFIS3 BFNIS HBSCI EIEE11 HBSCII Nav1.2 SCN2A1 SCN2A2 Na(v)1.2
FamilyBelongs to the sodium channel (TC 1.A.1.10) family. Nav1.2/SCN2A subfamily.
Sequence
MAQSVLVPPGPDSFRFFTRESLAAIEQRIAEEKAKRPKQERKDEDDENGPKPNSDLEAGKSLPFIYGDIPPEMVSVPLEDLDPYYINKKTFIVLNKGKAISRFSATPALYILTPFNPIRKLAIKILVHSLFNMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPDNSSFEINITSFFNNSLDGNGTTFNRTVSIFNWDEYIEDKSHFYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEEAQAAAAAASAESRDFSGAGGIGVFSESSSVASKLSSKSEKELKNRRKKKKQKEQSGEEEKNDRVRKSESEDSIRRKGFRFSLEGSRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRASLFSFRGRAKDIGSENDFADDEHSTFEDNDSRRDSLFVPHRHGERRHSNVSQASRASRVLPILPMNGKMHSAVDCNGVVSLVGGPSTLTSAGQLLPEGTTTETEIRKRRSSSYHVSMDLLEDPTSRQRAMSIASILTNTMEELEESRQKCPPCWYKFANMCLIWDCCKPWLKVKHLVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSSVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISNDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRMQKGIDFVKRKIREFIQKAFVRKQKALDEIKPLEDLNNKKDSCISNHTTIEIGKDLNYLKDGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESDMEESKEKLNATSSSEGSTVDIGAPAEGEQPEVEPEESLEPEACFTEDCVRKFKCCQISIEEGKGKLWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQVYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINYTTGEMFDVSVVNNYSECKALIESNQTARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQVFDISIMILICLNMVTMMVETDDQSQEMTNILYWINLVFIVLFTGECVLKLISLRYYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGPPDCDPDKDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFAKLSDFADALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYEPITTTLKRKQEEVSAIIIQRAYRRYLLKQKVKKVSSIYKKDKGKECDGTPIKEDTLIDKLNENSTPEKTDMTPSTTSPPSYDSVTKPEKEKFEKDKSEKEDKGKDIRESKK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp459700SCN2Asodium voltage-gated channel alpha subunit 29598VGNC:14354OMA, EggNOG
Macaque703298SCN2Asodium voltage-gated channel alpha subunit 29544Inparanoid, OMA
Mouse110876Scn2asodium channel, voltage-gated, type II, alpha10090MGI:98248OMA, EggNOG
Rat24766Scn2asodium voltage-gated channel alpha subunit 210116RGD:3632Inparanoid, OMA
Dog478773SCN2Asodium voltage-gated channel alpha subunit 29615VGNC:53105Inparanoid, OMA
Horse100051816SCN2Asodium voltage-gated channel alpha subunit 29796VGNC:22734Inparanoid, OMA
Cow539718SCN2Asodium voltage-gated channel alpha subunit 29913VGNC:34347Inparanoid, OMA
Pig100515171LOC100515171sodium channel protein type 2 subunit alpha9823Inparanoid, OMA
Opossum100016409SCN2Asodium voltage-gated channel alpha subunit 213616Inparanoid, OMA
Chicken395945SCN2Asodium voltage-gated channel alpha subunit 29031CGNC:49566Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    calcium channel    /    Sodium channel protein type 2 subunit alpha
protein    /    transporter    /    voltage-gated sodium channel    /    Sodium channel protein type 2 subunit alpha
protein    /    transporter    /    voltage-gated calcium channel    /    Sodium channel protein type 2 subunit alpha
protein    /    transporter    /    sodium channel    /    Sodium channel protein type 2 subunit alpha
protein    /    transporter    /    voltage-gated ion channel    /    Sodium channel protein type 2 subunit alpha
DTO Classes
protein    /    Ion channel    /    Sodium channel family    /    Nav1.2/SCN2A subfamily    /    Sodium channel protein type 2 subunit alpha

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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