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| Description | DNA-directed RNA polymerase I subunit RPA1 |
|---|
Gene and Protein Information
| Gene ID | 25885 |
|---|---|
| Uniprot Accession IDs | O95602 B7Z7T0 D6W5M0 Q0VG05 Q9UEH0 Q9UFT9 RNA polymerase I subunit A1 |
| Ensembl ID | ENSP00000263857 |
| Symbol | A190 RPA1 RPO14 AFDCIN RPA194 RPO1-4 |
| Family | Belongs to the RNA polymerase beta' chain family. |
| Sequence | MLISKNMPWRRLQGISFGMYSAEELKKLSVKSITNPRYLDSLGNPSANGLYDLALGPADSKEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLLLCQLRVLEVGALQAVYELERILNRFLEENPDPSASEIREELEQYTTEIVQNNLLGSQGAHVKNVCESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVHRTAGQKDSEPLGIEEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRFNPSVFFLDFLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTTDEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYPGIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRGLTDKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKETPRSVPGFNPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGKVLTCLARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYDEVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFLQPKQFPFLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHPNTLLRRGAFLSYSQKIQEAVKALKLESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAAACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEEKQNKFQVYQLRFQFLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVREIHPFIDDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGITRCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIRSNSSPLQQMTFETSFQFLKQATMLGSHDELRSPSACLVVGKVVRGGTGLFELKQPLR Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 459373 | POLR1A | RNA polymerase I subunit A | 9598 | VGNC:374 | OMA, EggNOG |
| Macaque | 696963 | POLR1A | RNA polymerase I subunit A | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 20019 | Polr1a | polymerase (RNA) I polypeptide A | 10090 | MGI:1096397 | Inparanoid, OMA, EggNOG |
| Rat | 83581 | Polr1a | RNA polymerase I subunit A | 10116 | RGD:620824 | Inparanoid, OMA, EggNOG |
| Dog | 475766 | POLR1A | RNA polymerase I subunit A | 9615 | VGNC:44788 | Inparanoid, OMA, EggNOG |
| Horse | 100067071 | POLR1A | RNA polymerase I subunit A | 9796 | VGNC:21668 | Inparanoid, OMA, EggNOG |
| Cow | 536316 | POLR1A | RNA polymerase I subunit A | 9913 | VGNC:33131 | Inparanoid, OMA, EggNOG |
| Pig | 100518066 | POLR1A | RNA polymerase I subunit A | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100018331 | POLR1A | RNA polymerase I subunit A | 13616 | Inparanoid, EggNOG | |
| Anole lizard | 100557301 | polr1a | RNA polymerase I subunit A | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100158635 | polr1a | polymerase (RNA) I polypeptide A | 8364 | XB-GENE-1005160 | Inparanoid, OMA, EggNOG |
| Zebrafish | 327078 | polr1a | RNA polymerase I subunit A | 7955 | ZDB-GENE-030131-5286 | Inparanoid, OMA |
| C. elegans | 175015 | rpoa-1 | DNA-directed RNA polymerase subunit | 6239 | Inparanoid, OMA, EggNOG | |
| Fruitfly | 36617 | RpI1 | RNA polymerase I subunit | 7227 | FBgn0019938 | Inparanoid, OMA, EggNOG |
| S.cerevisiae | 854519 | RPA190 | DNA-directed RNA polymerase I core subunit RPA190 | 4932 | S000005868 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / nucleic acid binding / DNA-directed RNA polymerase / DNA-directed RNA polymerase I subunit RPA1
protein / nucleic acid binding / nucleotidyltransferase / DNA-directed RNA polymerase I subunit RPA1
protein / nucleic acid binding / DNA-directed RNA polymerase / DNA-directed RNA polymerase I subunit RPA1
protein / nucleic acid binding / nucleotidyltransferase / DNA-directed RNA polymerase I subunit RPA1
DTO Classes
protein / Enzyme / Transferase / Nucleotidyltransferase / Polymerase / DNA-directed RNA polymerase / DNA-directed RNA polymerase I subunit RPA1
protein / Enzyme / Transferase / Nucleotidyltransferase / Polymerase / DNA-directed RNA polymerase / DNA-directed RNA polymerase I subunit RPA1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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