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RAPGEF1

DescriptionRap guanine nucleotide exchange factor 1

Gene and Protein Information

Gene ID2889
Uniprot Accession IDs Q13905 Q5JUE4 Q68DL3 Q8IV73
Ensembl ID ENSP00000361263
Symbol GRF2 C3G GRF2
Sequence
MDTDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKIPEKPVNKEATDRFLPEGYPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSSPASKPDGPAELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQTAWNLSPLPESLGESGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRRSAASQTADGSGCRVSYERHPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPVEFVGDFTAPESTGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQKNKLLMEVYGFSDSFSGVDSVQELAPPPALPPKQRQLEPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKSPDALESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVELTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp464812RAPGEF1Rap guanine nucleotide exchange factor 19598VGNC:4845OMA, EggNOG
Macaque715272RAPGEF1Rap guanine nucleotide exchange factor 19544Inparanoid, OMA, EggNOG
Mouse107746Rapgef1Rap guanine nucleotide exchange factor (GEF) 110090MGI:104580OMA, EggNOG
Rat63881Rapgef1Rap guanine nucleotide exchange factor 110116RGD:619793Inparanoid, OMA, EggNOG
Dog491286RAPGEF1Rap guanine nucleotide exchange factor 19615VGNC:45346OMA, EggNOG
Horse100069527RAPGEF1Rap guanine nucleotide exchange factor 19796VGNC:22179Inparanoid, OMA, EggNOG
Cow520454RAPGEF1Rap guanine nucleotide exchange factor 19913VGNC:33722OMA, EggNOG
Pig100511735RAPGEF1Rap guanine nucleotide exchange factor 19823OMA, EggNOG
Platypus100075047RAPGEF1Rap guanine nucleotide exchange factor 19258Inparanoid, OMA, EggNOG
Chicken417173RAPGEF1Rap guanine nucleotide exchange factor 19031CGNC:2714OMA, EggNOG
Xenopus733953rapgef1Rap guanine nucleotide exchange factor 18364XB-GENE-5729483OMA, EggNOG
Zebrafish558635rapgef1aRap guanine nucleotide exchange factor (GEF) 1a7955ZDB-GENE-081105-26OMA, EggNOG
Fruitfly31618C3GC3G guanyl-nucleotide exchange factor7227FBgn0259228Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    enzyme modulator    /    guanyl-nucleotide exchange factor    /    Rap guanine nucleotide exchange factor 1
DTO Classes
protein    /    Enzyme modulator    /    G-protein modulator    /    Guanyl-nucleotide exchange factor    /    Rap guanine nucleotide exchange factor 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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