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RAPGEF4

DescriptionRap guanine nucleotide exchange factor 4

Gene and Protein Information

Gene ID11069
Uniprot Accession IDs Q8WZA2 B2R7R3 B7Z283 B7Z3T6 B7Z912 O95636 Q8IXK6 Q8TAA4
Ensembl ID ENSP00000380271
Symbol CGEF2 EPAC2 EPAC CGEF2 EPAC2 EPAC 2 Nbla00496 CAMP-GEFII
Sequence
MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp459744RAPGEF4Rap guanine nucleotide exchange factor 49598VGNC:2797OMA, EggNOG
Macaque698148RAPGEF4Rap guanine nucleotide exchange factor 49544Inparanoid, OMA, EggNOG
Mouse56508Rapgef4Rap guanine nucleotide exchange factor (GEF) 410090MGI:1917723Inparanoid, OMA, EggNOG
Dog488402RAPGEF4Rap guanine nucleotide exchange factor 49615VGNC:53103Inparanoid, OMA, EggNOG
Horse100064121RAPGEF4Rap guanine nucleotide exchange factor 49796VGNC:22182Inparanoid, OMA, EggNOG
Cow537312RAPGEF4Rap guanine nucleotide exchange factor 49913VGNC:33725Inparanoid, OMA, EggNOG
Pig100511786RAPGEF4Rap guanine nucleotide exchange factor 49823OMA, EggNOG
Opossum100025283RAPGEF4Rap guanine nucleotide exchange factor 413616Inparanoid, OMA, EggNOG
Platypus100084234RAPGEF4Rap guanine nucleotide exchange factor 49258Inparanoid, OMA, EggNOG
Anole lizard100567156rapgef4Rap guanine nucleotide exchange factor 428377Inparanoid, OMA, EggNOG
Xenopusrapgef4Rap guanine nucleotide exchange factor 4 [Source:Xenbase;Acc:XB-GENE-6048644]8364OMA, EggNOG
Zebrafish559170rapgef4Rap guanine nucleotide exchange factor (GEF) 47955ZDB-GENE-070912-385Inparanoid, OMA, EggNOG
C. elegans176432epac-1Rap guanine nucleotide exchange factor 16239OMA, EggNOG
Fruitfly35588EpacExchange protein directly activated by cAMP7227FBgn0085421Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    enzyme modulator    /    guanyl-nucleotide exchange factor    /    Rap guanine nucleotide exchange factor 4
DTO Classes
protein    /    Enzyme modulator    /    G-protein modulator    /    Guanyl-nucleotide exchange factor    /    Rap guanine nucleotide exchange factor 4

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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