SPTLC1

DescriptionSerine palmitoyltransferase 1

Gene and Protein Information

Gene ID10558
Uniprot Accession IDs O15269 A8K681 Q5VWB4 Q96IX6
Ensembl ID ENSP00000262554
Symbol LCB1 HSN1 LBC1 LCB1 SPT1 SPTI HSAN1
FamilyBelongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Sequence
MATATEQWVLVEMVQALYEAPAYHLILEGILILWIIRLLFSKTYKLQERSDLTVKEKEELIEEWQPEPLVPPVPKDHPALNYNIVSGPPSHKTVVNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCGQIHKALQGISGLKVVGESLSPAFHLQLEESTGSREQDVRLLQEIVDQCMNRSIALTQARYLEKEEKCLPPPSIRVVVTVEQTEEELERAASTIKEVAQAVLL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp464590SPTLC1serine palmitoyltransferase long chain base subunit 19598VGNC:10108OMA, EggNOG
Macaque705324SPTLC1serine palmitoyltransferase long chain base subunit 19544OMA, EggNOG
Mouse268656Sptlc1serine palmitoyltransferase, long chain base subunit 110090MGI:1099431Inparanoid, OMA, EggNOG
Rat361213Sptlc1serine palmitoyltransferase, long chain base subunit 110116RGD:1307140Inparanoid, OMA, EggNOG
Dog484192SPTLC1serine palmitoyltransferase long chain base subunit 19615VGNC:46779Inparanoid, OMA, EggNOG
Horse100063025SPTLC1serine palmitoyltransferase long chain base subunit 19796VGNC:23559Inparanoid, OMA, EggNOG
Cow614165SPTLC1serine palmitoyltransferase long chain base subunit 19913VGNC:35256Inparanoid, OMA, EggNOG
Pig100739638SPTLC1serine palmitoyltransferase long chain base subunit 19823OMA, EggNOG
Opossum100027691SPTLC1serine palmitoyltransferase long chain base subunit 113616Inparanoid, OMA, EggNOG
Chicken426145SPTLC1serine palmitoyltransferase long chain base subunit 19031CGNC:10137Inparanoid, OMA, EggNOG
Anole lizard100553895sptlc1serine palmitoyltransferase long chain base subunit 128377Inparanoid, OMA, EggNOG
Xenopus779626sptlc1serine palmitoyltransferase, long chain base subunit 18364XB-GENE-1004880Inparanoid, OMA, EggNOG
Zebrafish553981sptlc1serine palmitoyltransferase, long chain base subunit 17955ZDB-GENE-050522-61Inparanoid, OMA, EggNOG
C. elegans173389sptl-1Serine Palmitoyl Transferase famiLy6239Inparanoid, OMA
Fruitfly36448Spt-ISerine palmitoyltransferase subunit I7227FBgn0086532Inparanoid, EggNOG
S.cerevisiae855342LCB1serine C-palmitoyltransferase LCB14932S000004911Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transferase    /    transaminase    /    Serine palmitoyltransferase 1
DTO Classes
protein    /    Enzyme    /    Transferase    /    Transaminase    /    Serine palmitoyltransferase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

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