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IARS2

DescriptionIsoleucine--tRNA ligase, mitochondrial

Gene and Protein Information

Gene ID55699
Uniprot Accession IDs Q9NSE4 B2RPG8 Q1M2P9 Q6PI85 Q7L439 Q86WU9 Q96D91 Q9H9Q8 Q9NW42
Ensembl ID ENSP00000355889
Symbol ILERS CAGSSS
FamilyBelongs to the class-I aminoacyl-tRNA synthetase family.
Sequence
MRWGLRPRGPGAAALATARSLWGTPRLPCSPGWQGATKRLLVRSVSGASNHQPNSNSGRYRDTVLLPQTSFPMKLLGRQQPDTELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAADKVASVASTLETTFETISTLSGVDLENGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDGVFTDVAGPELQNKAVLEEGTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFINITDIKTAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSGTSWSYVLPGPDQRADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNAARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYKVITVIEPGLLFEIIEMLQSEETSSTSQLNELMMASESTLLAQEPREMTADVIELKGKFLINLEGGDIREESSYKVIVMPTTKEKCPRCWKYTAESSDTLCPRCAEVVSGK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Mouse381314Iars2isoleucine-tRNA synthetase 2, mitochondrial10090MGI:1919586Inparanoid, OMA
Dog478963IARS2isoleucyl-tRNA synthetase 2, mitochondrial9615VGNC:41850Inparanoid, OMA
Horse100049915IARS2isoleucyl-tRNA synthetase 2, mitochondrial9796VGNC:18922Inparanoid, OMA
Cow533057IARS2isoleucyl-tRNA synthetase 2, mitochondrial9913VGNC:30019Inparanoid, OMA
Opossum100024337IARS2isoleucyl-tRNA synthetase 2, mitochondrial13616Inparanoid, OMA
Platypus100080817IARS2isoleucyl-tRNA synthetase 2, mitochondrial9258Inparanoid, OMA
Chicken421346IARS2isoleucyl-tRNA synthetase 2, mitochondrial9031CGNC:7282Inparanoid, OMA
Anole lizard100559437iars2isoleucyl-tRNA synthetase 2, mitochondrial28377Inparanoid, OMA
Zebrafish100001219iars2isoleucyl-tRNA synthetase 2, mitochondrial7955ZDB-GENE-030616-608Inparanoid, OMA
S.cerevisiae856067ISM1isoleucine--tRNA ligase ISM14932S000005961Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    ligase    /    aminoacyl-tRNA synthetase    /    Isoleucine--tRNA ligase, mitochondrial
DTO Classes
protein    /    Enzyme    /    Ligase    /    Aminoacyl-tRNA synthetase    /    Isoleucine--tRNA ligase, mitochondrial

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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