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| Description | Non-receptor tyrosine-protein kinase TYK2 |
|---|
Gene and Protein Information
| Gene ID | 7297 |
|---|---|
| Uniprot Accession IDs | P29597 Q6QB10 Q96CH0 |
| Ensembl ID | ENSP00000431885 |
| Symbol | JTK1 IMD35 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. |
| Sequence | MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 455703 | TYK2 | tyrosine kinase 2 | 9598 | VGNC:2210 | OMA, EggNOG |
| Macaque | 574130 | TYK2 | tyrosine kinase 2 | 9544 | OMA, EggNOG | |
| Mouse | 54721 | Tyk2 | tyrosine kinase 2 | 10090 | MGI:1929470 | Inparanoid, OMA, EggNOG |
| Rat | 100361294 | Tyk2 | tyrosine kinase 2 | 10116 | RGD:2320469 | Inparanoid, OMA, EggNOG |
| Dog | 476714 | TYK2 | tyrosine kinase 2 | 9615 | VGNC:48024 | Inparanoid, OMA, EggNOG |
| Horse | TYK2 | tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440] | 9796 | OMA, EggNOG | ||
| Cow | 512484 | TYK2 | tyrosine kinase 2 | 9913 | VGNC:36548 | Inparanoid, OMA, EggNOG |
| Pig | 397363 | TYK2 | tyrosine kinase 2 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100012931 | TYK2 | tyrosine kinase 2 | 13616 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100566727 | tyk2 | tyrosine kinase 2 | 28377 | Inparanoid, OMA | |
| Xenopus | 100489432 | tyk2 | tyrosine kinase 2 | 8364 | XB-GENE-993652 | Inparanoid, OMA |
| Zebrafish | 100536675 | tyk2 | tyrosine kinase 2 | 7955 | ZDB-GENE-071116-4 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / JAKA family / Non-receptor tyrosine-protein kinase tyk2
protein / Kinase / Protein kinase / TK group / JAKA family / Non-receptor tyrosine-protein kinase tyk2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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