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| Description | Insulin-degrading enzyme |
|---|
Gene and Protein Information
| Gene ID | 3416 |
|---|---|
| Uniprot Accession IDs | P14735 B2R721 B7ZAU2 D3DR35 Q5T5N2 |
| Ensembl ID | ENSP00000265986 |
| Symbol | INSULYSIN |
| Family | Belongs to the peptidase M16 family. |
| Sequence | MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 450608 | IDE | insulin degrading enzyme | 9598 | VGNC:7230 | OMA, EggNOG |
| Macaque | 698640 | IDE | insulin degrading enzyme | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 15925 | Ide | insulin degrading enzyme | 10090 | MGI:96412 | Inparanoid, OMA, EggNOG |
| Rat | 25700 | Ide | insulin degrading enzyme | 10116 | RGD:2861 | Inparanoid, OMA, EggNOG |
| Dog | 477768 | IDE | insulin degrading enzyme | 9615 | VGNC:41863 | Inparanoid, OMA, EggNOG |
| Horse | 100071303 | IDE | insulin degrading enzyme | 9796 | VGNC:18936 | Inparanoid, OMA, EggNOG |
| Cow | 523752 | IDE | insulin degrading enzyme | 9913 | VGNC:30033 | Inparanoid, OMA, EggNOG |
| Pig | 100155309 | IDE | insulin degrading enzyme | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100024067 | IDE | insulin degrading enzyme | 13616 | Inparanoid, EggNOG | |
| Platypus | 100074945 | IDE | insulin degrading enzyme | 9258 | Inparanoid, OMA, EggNOG | |
| Zebrafish | 561390 | ide | insulin-degrading enzyme | 7955 | ZDB-GENE-070410-85 | Inparanoid, OMA |
| C. elegans | 182987 | C28F5.4 | Putative zinc protease C28F5.4 | 6239 | Inparanoid, OMA | |
| C. elegans | 178966 | F44E7.4 | hypothetical protein | 6239 | OMA, EggNOG | |
| Fruitfly | 40248 | Ide | Insulin degrading metalloproteinase | 7227 | FBgn0001247 | Inparanoid, OMA, EggNOG |
| S.cerevisiae | 851105 | STE23 | metalloendopeptidase | 4932 | S000004381 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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