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| Description | Histone-lysine N-methyltransferase KMT5B |
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Gene and Protein Information
| Gene ID | 51111 |
|---|---|
| Uniprot Accession IDs | Q4FZB7 B7WNX7 Q3SX56 Q4V775 Q6P150 Q96E44 Q9BUL0 Q9H022 Q9H2K3 Q9NXV3 Q9Y393 |
| Ensembl ID | ENSP00000305899 |
| Symbol | SUV420H1 CGI85 MRD51 CGI-85 SUV420H1 |
| Family | Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily. |
| Sequence | MKWLGESKIMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGFEGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFSHNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 451378 | KMT5B | lysine methyltransferase 5B | 9598 | VGNC:7658 | OMA, EggNOG |
| Macaque | 710481 | KMT5B | lysine methyltransferase 5B | 9544 | OMA, EggNOG | |
| Mouse | 225888 | Kmt5b | lysine methyltransferase 5B | 10090 | MGI:2444557 | Inparanoid, OMA, EggNOG |
| Rat | 361688 | Kmt5b | lysine methyltransferase 5B | 10116 | RGD:1311637 | Inparanoid, OMA, EggNOG |
| Dog | 483690 | KMT5B | lysine methyltransferase 5B | 9615 | VGNC:42494 | OMA, EggNOG |
| Horse | 100053438 | KMT5B | lysine methyltransferase 5B | 9796 | VGNC:19496 | OMA, EggNOG |
| Opossum | 100010281 | KMT5B | lysine methyltransferase 5B | 13616 | OMA, EggNOG | |
| Chicken | 425119 | KMT5B | lysine methyltransferase 5B | 9031 | CGNC:10552 | OMA, EggNOG |
| Anole lizard | 100553817 | kmt5b | lysine methyltransferase 5B | 28377 | OMA, EggNOG | |
| Zebrafish | 572849 | kmt5b | lysine methyltransferase 5B | 7955 | ZDB-GENE-041114-22 | Inparanoid, OMA, EggNOG |
| C. elegans | 174045 | set-4 | Histone-lysine N-methyltransferase Suv4-20 | 6239 | Inparanoid, EggNOG |
Protein Classes
DTO Classes
protein / Epigenetic regulator / Writer / Protein methyltransferase / Histone-lysine N-methyltransferase KMT5B
protein / Epigenetic regulator / Writer / Protein methyltransferase / Histone-lysine N-methyltransferase KMT5B
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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