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| Description | Receptor-type tyrosine-protein kinase FLT3 |
|---|
Gene and Protein Information
| Gene ID | 2322 |
|---|---|
| Uniprot Accession IDs | P36888 A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414 |
| Ensembl ID | ENSP00000241453 |
| Symbol | CD135 FLK2 STK1 FLK2 STK1 CD135 FLK-2 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. |
| Sequence | MPALARDGGQLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNVDGRVSECPHTYQNRRPFSREMDLGLLSPQAQVEDS Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 452508 | FLT3 | fms related tyrosine kinase 3 | 9598 | VGNC:7288 | OMA, EggNOG |
| Macaque | 721712 | FLT3 | fms related tyrosine kinase 3 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 14255 | Flt3 | FMS-like tyrosine kinase 3 | 10090 | MGI:95559 | Inparanoid, OMA, EggNOG |
| Rat | 140635 | Flt3 | fms-related tyrosine kinase 3 | 10116 | RGD:61308 | Inparanoid, OMA |
| Dog | 486025 | FLT3 | fms related tyrosine kinase 3 | 9615 | VGNC:40908 | Inparanoid, OMA, EggNOG |
| Horse | 100061780 | FLT3 | fms related tyrosine kinase 3 | 9796 | VGNC:18068 | Inparanoid, OMA, EggNOG |
| Cow | 512700 | FLT3 | fms related tyrosine kinase 3 | 9913 | VGNC:29042 | Inparanoid, OMA, EggNOG |
| Pig | 100515445 | FLT3 | fms related tyrosine kinase 3 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100025262 | FLT3 | fms related tyrosine kinase 3 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100090467 | FLT3 | fms related tyrosine kinase 3 | 9258 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100557093 | flt3 | fms related tyrosine kinase 3 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | FLT3 | fms related tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3765] | 8364 | OMA, EggNOG | ||
| Zebrafish | 566708 | flt3 | fms-related tyrosine kinase 3 | 7955 | ZDB-GENE-050114-4 | Inparanoid, OMA, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / PDGFR family / Receptor-type tyrosine-protein kinase flt3
protein / Kinase / Protein kinase / TK group / PDGFR family / Receptor-type tyrosine-protein kinase flt3
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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