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| Description | Alpha-ketoglutarate-dependent dioxygenase FTO |
|---|
Gene and Protein Information
| Gene ID | 79068 |
|---|---|
| Uniprot Accession IDs | Q9C0B1 A2RUH1 B2RNS0 Q0P676 Q7Z785 |
| Ensembl ID | ENSP00000418823 |
| Symbol | KIAA1752 GDFD ALKBH9 BMIQ14 |
| Family | Belongs to the fto family. |
| Sequence | MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 454090 | FTO | FTO, alpha-ketoglutarate dependent dioxygenase | 9598 | VGNC:14493 | OMA, EggNOG |
| Macaque | 703724 | FTO | FTO, alpha-ketoglutarate dependent dioxygenase | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 26383 | Fto | fat mass and obesity associated | 10090 | MGI:1347093 | Inparanoid, OMA, EggNOG |
| Rat | 291905 | Fto | FTO, alpha-ketoglutarate dependent dioxygenase | 10116 | RGD:1305121 | Inparanoid, OMA, EggNOG |
| Dog | 478125 | FTO | FTO, alpha-ketoglutarate dependent dioxygenase | 9615 | VGNC:41003 | Inparanoid, OMA, EggNOG |
| Horse | 100060565 | FTO | FTO, alpha-ketoglutarate dependent dioxygenase | 9796 | VGNC:18149 | Inparanoid, OMA, EggNOG |
| Cow | 618622 | FTO | FTO, alpha-ketoglutarate dependent dioxygenase | 9913 | VGNC:29138 | Inparanoid, OMA, EggNOG |
| Opossum | 100019431 | FTO | FTO, alpha-ketoglutarate dependent dioxygenase | 13616 | Inparanoid, EggNOG | |
| Anole lizard | 100556980 | fto | FTO, alpha-ketoglutarate dependent dioxygenase | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 550027 | fto | fat mass and obesity associated | 8364 | XB-GENE-972564 | Inparanoid, OMA, EggNOG |
| Zebrafish | 553363 | fto | fat mass and obesity associated | 7955 | ZDB-GENE-061108-1 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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