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PIKFYVE

Description1-phosphatidylinositol 3-phosphate 5-kinase

Gene and Protein Information

Gene ID200576
Uniprot Accession IDs Q9Y2I7 Q08AR7 Q08AR8 Q53ST3 Q53T36 Q8N5H0 Q8NB67 Phosphatidylinositol 3-phosphate 5-kinase
Ensembl ID ENSP00000264380
Symbol KIAA0981 PIP5K3 CFD FAB1 HEL37 PIP5K PIP5K3 ZFYVE29
Sequence
MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERAEGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALDTRRKAEPTFGGHDPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQKEYLISDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENGEKQAMERLLSANHNHMMALLQQLLHSDSLSSSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMSSCIKNPKILLLKCSIEYLYREETKFTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLMQNPSFHSLIEGRGHEGAVQEQYGGGSIPWDPDIPPESLPCDDSSLLELRIVFEKGEQENKNLPQAVASVKHQEHSTTACPAGLPCAFFAPVPESLLPLPVDDQQDALGSEQPETLQQTVVLQDPKSQIRAFRDPLQDDTGLYVTEEVTSSEDKRKTYSLAFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDYFAEQVYWSPLLNKEFKEMENRRKKQLLRDLSGLQGMNGSIQAKSIQVLPSHELVSTRIAEHLGDSQSLGRMLADYRARGGRIQPKNSDPFAHSKDASSTSSGQSGSKNEGDEERGLILSDAVWSTKVDCLNPINHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLERYCFRPSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGYQHTILTYSWCRICKQVTPVVALSNESWSMSFAKYLELRFYGHQYTRRANAEPCGHSIHHDYHQYFSYNQMVASFSYSPIRLLEVCVPLPKIFIKRQAPLKVSLLQDLKDFFQKVSQVYVAIDERLASLKTDTFSKTREEKMEDIFAQKEMEEGEFKNWIEKMQARLMSSSVDTPQQLQSVFESLIAKKQSLCEVLQAWNNRLQDLFQQEKGRKRPSVPPSPGRLRQGEESKISAMDASPRNISPGLQNGEKEDRFLTTLSSQSSTSSTHLQLPTPPEVMSEQSVGGPPELDTASSSEDVFDGHLLGSTDSQVKEKSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEYRNALEELSKATQWNSAEEGLPTNSTSDSRPKSSSPIRLPEMSGGQTNRTTETEPQPTKKASGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGTENQGVEPQDEVDGGDTQKKQLINPHVELQFSDANAKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLGLNC
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp459908PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9598VGNC:2754OMA, EggNOG
Macaque710115PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9544Inparanoid, OMA, EggNOG
Mouse18711Pikfyvephosphoinositide kinase, FYVE type zinc finger containing10090MGI:1335106Inparanoid, OMA, EggNOG
Rat316457Pikfyvephosphoinositide kinase, FYVE-type zinc finger containing10116RGD:1592067Inparanoid, OMA, EggNOG
Dog478890PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9615VGNC:44564Inparanoid, OMA, EggNOG
Horse100066445PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9796VGNC:21455Inparanoid, OMA, EggNOG
Cow790873PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9913VGNC:32898Inparanoid, OMA, EggNOG
Pig100521692PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9823Inparanoid, OMA, EggNOG
Opossum100013564PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing13616Inparanoid, OMA, EggNOG
Platypus100076756PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9258Inparanoid, EggNOG
Chicken424114PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9031CGNC:6712Inparanoid, OMA, EggNOG
Anole lizard100566486pikfyvephosphoinositide kinase, FYVE-type zinc finger containing28377Inparanoid, OMA, EggNOG
Zebrafish337690pikfyvephosphoinositide kinase, FYVE finger containing7955ZDB-GENE-030131-9636Inparanoid, OMA, EggNOG
C. elegans181428ppk-3PIP Kinase6239Inparanoid, OMA, EggNOG
Fruitfly37033fab1fab1 kinase7227FBgn0028741Inparanoid, EggNOG
S.cerevisiae850574FAB11-phosphatidylinositol-3-phosphate 5-kinase4932S000001915Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Non-protein kinase    /    Lipid kinase    /    1-phosphatidylinositol 3-phosphate 5-kinase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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