FEN1

DescriptionFlap endonuclease 1

Gene and Protein Information

Gene ID2237
Uniprot Accession IDs P39748 FEN-1
Ensembl ID ENSP00000305480
Symbol RAD2 MF1 RAD2 FEN-1
FamilyBelongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Sequence
MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEPKGSTKKKAKTGAAGKFKRGK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp451242FEN1flap structure-specific endonuclease 19598VGNC:6752OMA, EggNOG
Macaque722348FEN1flap structure-specific endonuclease 19544Inparanoid, OMA, EggNOG
Mouse14156Fen1flap structure specific endonuclease 110090MGI:102779Inparanoid, OMA, EggNOG
Rat84490Fen1flap structure-specific endonuclease 110116RGD:621821Inparanoid, OMA, EggNOG
Dog476063FEN1flap structure-specific endonuclease 19615VGNC:40817Inparanoid, OMA, EggNOG
Horse100059838FEN1flap structure-specific endonuclease 19796VGNC:17990Inparanoid, OMA, EggNOG
Cow616242FEN1flap structure-specific endonuclease 19913VGNC:28947Inparanoid, OMA, EggNOG
Pig100517749FEN1flap structure-specific endonuclease 19823Inparanoid, OMA, EggNOG
Opossum100012289FEN1flap structure-specific endonuclease 113616Inparanoid, OMA, EggNOG
Anole lizardFEN1flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650]28377Inparanoid, OMA, EggNOG
Xenopus549759fen1flap structure-specific endonuclease 18364XB-GENE-955518Inparanoid, OMA, EggNOG
Zebrafish386707fen1flap structure-specific endonuclease 17955ZDB-GENE-031112-11Inparanoid, OMA, EggNOG
C. elegans171917crn-1Flap endonuclease 16239Inparanoid, OMA
Fruitfly36887Fen1Flap endonuclease 17227FBgn0025832Inparanoid, OMA, EggNOG
S.cerevisiae853747RAD27multifunctional nuclease RAD274932S000001596Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    damaged DNA-binding protein    /    Flap endonuclease 1
protein    /    nucleic acid binding    /    exodeoxyribonuclease    /    Flap endonuclease 1
protein    /    nucleic acid binding    /    nuclease    /    Flap endonuclease 1
protein    /    nucleic acid binding    /    endodeoxyribonuclease    /    Flap endonuclease 1
protein    /    nucleic acid binding    /    hydrolase    /    Flap endonuclease 1
DTO Classes
protein    /    Enzyme    /    Nuclease    /    Exodeoxyribonuclease    /    Flap endonuclease 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

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