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| Description | Cystic fibrosis transmembrane conductance regulator |
|---|
Gene and Protein Information
| Gene ID | 1080 |
|---|---|
| Uniprot Accession IDs | P13569 Q20BG8 Q20BH2 Q2I0A1 Q2I102 CFTR |
| Ensembl ID | ENSP00000003084 |
| Symbol | ABCC7 CF MRP7 ABC35 ABCC7 CFTR/MRP TNR-CFTR dJ760C5.1 |
| Family | Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily. |
| Sequence | MQRSPLEKASVVSKLFFSWTRPILRKGYRQRLELSDIYQIPSVDSADNLSEKLEREWDRELASKKNPKLINALRRCFFWRFMFYGIFLYLGEVTKAVQPLLLGRIIASYDPDNKEERSIAIYLGIGLCLLFIVRTLLLHPAIFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQLVSLLSNNLNKFDEGLALAHFVWIAPLQVALLMGLIWELLQASAFCGLGFLIVLALFQAGLGRMMMKYRDQRAGKISERLVITSEMIENIQSVKAYCWEEAMEKMIENLRQTELKLTRKAAYVRYFNSSAFFFSGFFVVFLSVLPYALIKGIILRKIFTTISFCIVLRMAVTRQFPWAVQTWYDSLGAINKIQDFLQKQEYKTLEYNLTTTEVVMENVTAFWEEGFGELFEKAKQNNNNRKTSNGDDSLFFSNFSLLGTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLQPDFSSKLMGCDSFDQFSAERRNSILTETLHRFSLEGDAPVSWTETKKQSFKQTGEFGEKRKNSILNPINSIRKFSIVQKTPLQMNGIEEDSDEPLERRLSLVPDSEQGEAILPRISVISTGPTLQARRRQSVLNLMTHSVNQGQNIHRKTTASTRKVSLAPQANLTELDIYSRRLSQETGLEISEEINEEDLKECFFDDMESIPAVTTWNTYLRYITVHKSLIFVLIWCLVIFLAEVAASLVVLWLLGNTPLQDKGNSTHSRNNSYAVIITSTSSYYVFYIYVGVADTLLAMGFFRGLPLVHTLITVSKILHHKMLHSVLQAPMSTLNTLKAGGILNRFSKDIAILDDLLPLTIFDFIQLLLIVIGAIAVVAVLQPYIFVATVPVIVAFIMLRAYFLQTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKALNLHTANWFLYLSTLRWFQMRIEMIFVIFFIAVTFISILTTGEGEGRVGIILTLAMNIMSTLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEGKPTKSTKPYKNGQLSKVMIIENSHVKKDDIWPSGGQMTVKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTEGEIQIDGVSWDSITLQQWRKAFGVIPQKVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLLNERSLFRQAISPSDRVKLFPHRNSSKCKSKPQIAALKEETEEEVQDTRL Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 463674 | CFTR | cystic fibrosis transmembrane conductance regulator | 9598 | Inparanoid, OMA, EggNOG | |
| Macaque | 574346 | CFTR | cystic fibrosis transmembrane conductance regulator | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 12638 | Cftr | cystic fibrosis transmembrane conductance regulator | 10090 | MGI:88388 | Inparanoid, OMA, EggNOG |
| Rat | 24255 | Cftr | cystic fibrosis transmembrane conductance regulator | 10116 | RGD:2332 | Inparanoid, OMA |
| Dog | 492302 | CFTR | cystic fibrosis transmembrane conductance regulator | 9615 | VGNC:39180 | Inparanoid, OMA, EggNOG |
| Horse | 100071259 | CFTR | cystic fibrosis transmembrane conductance regulator | 9796 | VGNC:16468 | Inparanoid, OMA, EggNOG |
| Cow | 281067 | CFTR | cystic fibrosis transmembrane conductance regulator | 9913 | VGNC:50053 | Inparanoid, OMA, EggNOG |
| Pig | 403154 | CFTR | cystic fibrosis transmembrane conductance regulator | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100014119 | CFTR | cystic fibrosis transmembrane conductance regulator | 13616 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100559531 | cftr | cystic fibrosis transmembrane conductance regulator | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100486085 | cftr | cystic fibrosis transmembrane conductance regulator | 8364 | XB-GENE-853972 | Inparanoid, OMA, EggNOG |
| Zebrafish | 559080 | cftr | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 7955 | ZDB-GENE-050517-20 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / transporter / ATP-binding cassette (ABC) transporter / Cystic fibrosis transmembrane conductance regulator
protein / transporter / ATP-binding cassette (ABC) transporter / Cystic fibrosis transmembrane conductance regulator
DTO Classes
protein / Ion channel / ABCC family / CFTR transporter subfamily / Cystic fibrosis transmembrane conductance regulator
protein / Ion channel / ABCC family / CFTR transporter subfamily / Cystic fibrosis transmembrane conductance regulator
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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