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EIF5B

DescriptionEukaryotic translation initiation factor 5B

Gene and Protein Information

Gene ID9669
Uniprot Accession IDs O60841 O95805 Q53RV7 Q53SI8 Q9UF81 Q9UMN7 eIF-5B
Ensembl ID ENSP00000289371
Symbol IF2 KIAA0741 IF2
FamilyBelongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Sequence
MGKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDTGKTKILDKLRHTHVQDGEAGGITQQIGATNVPLEAINEQTKMIKNFDRENVRIPGMLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIESINLLKSKKCPFIVALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEERAKAIIVEFAQQGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVELTQTMLSKRLAHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTIIVPGVEGPIVTQIRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKEDEIPVLKDELIHELKQTLNAIKLEEKGVYVQASTLGSLEALLEFLKTSEVPYAGINIGPVHKKDVMKASVMLEHDPQYAVILAFDVRIERDAQEMADSLGVRIFSAEIIYHLFDAFTKYRQDYKKQKQEEFKHIAVFPCKIKILPQYIFNSRDPIVMGVTVEAGQVKQGTPMCVPSKNFVDIGIVTSIEINHKQVDVAKKGQEVCVKIEPIPGESPKMFGRHFEATDILVSKISRQSIDALKDWFRDEMQKSDWQLIVELKKVFEII
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp459443EIF5Beukaryotic translation initiation factor 5B9598VGNC:236OMA, EggNOG
Macaque714129EIF5Beukaryotic translation initiation factor 5B9544Inparanoid, OMA, EggNOG
Mouse226982Eif5beukaryotic translation initiation factor 5B10090MGI:2441772Inparanoid, OMA, EggNOG
RatAABR07043748.1-10116OMA, EggNOG
Dog474556EIF5Beukaryotic translation initiation factor 5B9615VGNC:40294Inparanoid, OMA, EggNOG
Horse100050422EIF5Beukaryotic translation initiation factor 5B9796VGNC:17512Inparanoid, OMA, EggNOG
Cow532850EIF5Beukaryotic translation initiation factor 5B9913VGNC:28420Inparanoid, OMA, EggNOG
Pig100520783EIF5Beukaryotic translation initiation factor 5B9823Inparanoid, OMA, EggNOG
Opossum100014602EIF5Beukaryotic translation initiation factor 5B13616Inparanoid, OMA, EggNOG
PlatypusEIF5Beukaryotic translation initiation factor 5B [Source:HGNC Symbol;Acc:HGNC:30793]9258OMA, EggNOG
Chicken395514EIF5Beukaryotic translation initiation factor 5B9031CGNC:12572Inparanoid, OMA, EggNOG
Anole lizard100553402eif5beukaryotic translation initiation factor 5B28377Inparanoid, OMA, EggNOG
Xenopus100492012eif5beukaryotic translation initiation factor 5B8364XB-GENE-6258156Inparanoid, OMA, EggNOG
Zebrafish561194eif5beukaryotic translation initiation factor 5B7955ZDB-GENE-050208-20Inparanoid, OMA, EggNOG
C. elegans175353iffb-1Initiation Factor Five B (eIF5B)6239Inparanoid, OMA, EggNOG
Fruitfly44261eIF5BCG10840 gene product from transcript CG10840-RE7227FBgn0026259Inparanoid, EggNOG
S.cerevisiae851196FUN12translation initiation factor eIF5B4932S000000033Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    translation initiation factor    /    Eukaryotic translation initiation factor 5B
protein    /    nucleic acid binding    /    translation elongation factor    /    Eukaryotic translation initiation factor 5B
protein    /    nucleic acid binding    /    hydrolase    /    Eukaryotic translation initiation factor 5B
protein    /    nucleic acid binding    /    G-protein    /    Eukaryotic translation initiation factor 5B
DTO Classes
protein    /    Enzyme    /    Hydrolase    /    Eukaryotic translation initiation factor 5B

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

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