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SCN11A

DescriptionSodium channel protein type 11 subunit alpha

Gene and Protein Information

Gene ID11280
Uniprot Accession IDs Q9UI33 A6NN05 C9JD48 C9JR31 Q68K15 Q8NDX3 Q9UHE0 Q9UHM0
Ensembl ID ENSP00000307599
Symbol SCN12A SNS2 NaN PN5 FEPS3 HSAN7 SNS-2 NAV1.9 SCN12A
FamilyBelongs to the sodium channel (TC 1.A.1.10) family. Nav1.9/SCN11A subfamily.
Sequence
MDDRCYPVIFPDERNFRPFTSDSLAAIEKRIAIQKEKKKSKDQTGEVPQPRPQLDLKASRKLPKLYGDIPRELIGKPLEDLDPFYRNHKTFMVLNRKRTIYRFSAKHALFIFGPFNSIRSLAIRVSVHSLFSMFIIGTVIINCVFMATGPAKNSNSNNTDIAECVFTGIYIFEALIKILARGFILDEFSFLRDPWNWLDSIVIGIAIVSYIPGITIKLLPLRTFRVFRALKAISVVSRLKVIVGALLRSVKKLVNVIILTFFCLSIFALVGQQLFMGSLNLKCISRDCKNISNPEAYDHCFEKKENSPEFKMCGIWMGNSACSIQYECKHTKINPDYNYTNFDNFGWSFLAMFRLMTQDSWEKLYQQTLRTTGLYSVFFFIVVIFLGSFYLINLTLAVVTMAYEEQNKNVAAEIEAKEKMFQEAQQLLKEEKEALVAMGIDRSSLTSLETSYFTPKKRKLFGNKKRKSFFLRESGKDQPPGSDSDEDCQKKPQLLEQTKRLSQNLSLDHFDEHGDPLQRQRALSAVSILTITMKEQEKSQEPCLPCGENLASKYLVWNCCPQWLCVKKVLRTVMTDPFTELAITICIIINTVFLAMEHHKMEASFEKMLNIGNLVFTSIFIAEMCLKIIALDPYHYFRRGWNIFDSIVALLSFADVMNCVLQKRSWPFLRSFRVLRVFKLAKSWPTLNTLIKIIGNSVGALGSLTVVLVIVIFIFSVVGMQLFGRSFNSQKSPKLCNPTGPTVSCLRHWHMGDFWHSFLVVFRILCGEWIENMWECMQEANASSSLCVIVFILITVIGKLVVLNLFIALLLNSFSNEERNGNLEGEARKTKVQLALDRFRRAFCFVRHTLEHFCHKWCRKQNLPQQKEVAGGCAAQSKDIIPLVMEMKRGSETQEELGILTSVPKTLGVRHDWTWLAPLAEEEDDVEFSGEDNAQRITQPEPEQQAYELHQENKKPTSQRVQSVEIDMFSEDEPHLTIQDPRKKSDVTSILSECSTIDLQDGFGWLPEMVPKKQPERCLPKGFGCCFPCCSVDKRKPPWVIWWNLRKTCYQIVKHSWFESFIIFVILLSSGALIFEDVHLENQPKIQELLNCTDIIFTHIFILEMVLKWVAFGFGKYFTSAWCCLDFIIVIVSVTTLINLMELKSFRTLRALRPLRALSQFEGMKVVVNALIGAIPAILNVLLVCLIFWLVFCILGVYFFSGKFGKCINGTDSVINYTIITNKSQCESGNFSWINQKVNFDNVGNAYLALLQVATFKGWMDIIYAAVDSTEKEQQPEFESNSLGYIYFVVFIIFGSFFTLNLFIGVIIDNFNQQQKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKCQGLVFDIVTSQIFDIIIISLIILNMISMMAESYNQPKAMKSILDHLNWVFVVIFTLECLIKIFALRQYYFTNGWNLFDCVVVLLSIVSTMISTLENQEHIPFPPTLFRIVRLARIGRILRLVRAARGIRTLLFALMMSLPSLFNIGLLLFLIMFIYAILGMNWFSKVNPESGIDDIFNFKTFASSMLCLFQISTSAGWDSLLSPMLRSKESCNSSSENCHLPGIATSYFVSYIIISFLIVVNMYIAVILENFNTATEESEDPLGEDDFDIFYEVWEKFDPEATQFIKYSALSDFADALPEPLRVAKPNKYQFLVMDLPMVSEDRLHCMDILFAFTARVLGGSDGLDSMKAMMEEKFMEANPLKKLYEPIVTTTKRKEEERGAAIIQKAFRKYMMKVTKGDQGDQNDLENGPHSPLQTLCNGDLSSFGVAKGKVHCD
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp460275SCN11Asodium voltage-gated channel alpha subunit 119598VGNC:12182OMA, EggNOG
Macaque695258SCN11Asodium voltage-gated channel alpha subunit 119544OMA, EggNOG
Mouse24046Scn11asodium channel, voltage-gated, type XI, alpha10090MGI:1345149Inparanoid, OMA, EggNOG
Rat29701Scn11asodium voltage-gated channel alpha subunit 1110116RGD:3630Inparanoid, OMA
Dog485593SCN11Asodium voltage-gated channel alpha subunit 119615VGNC:45914Inparanoid, OMA
Horse100068480SCN11Asodium voltage-gated channel alpha subunit 119796VGNC:22731Inparanoid, OMA, EggNOG
Cow535956SCN11Asodium voltage-gated channel alpha subunit 119913VGNC:34344Inparanoid, OMA
OpossumSCN11Asodium voltage-gated channel alpha subunit 11 [Source:HGNC Symbol;Acc:HGNC:10583]13616Inparanoid, OMA, EggNOG
PlatypusSCN11Asodium voltage-gated channel alpha subunit 11 [Source:HGNC Symbol;Acc:HGNC:10583]9258OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    calcium channel    /    Sodium channel protein type 11 subunit alpha
protein    /    transporter    /    voltage-gated sodium channel    /    Sodium channel protein type 11 subunit alpha
protein    /    transporter    /    voltage-gated calcium channel    /    Sodium channel protein type 11 subunit alpha
protein    /    transporter    /    sodium channel    /    Sodium channel protein type 11 subunit alpha
protein    /    transporter    /    voltage-gated ion channel    /    Sodium channel protein type 11 subunit alpha
DTO Classes
protein    /    Ion channel    /    Sodium channel family    /    Nav1.9/SCN11A subfamily    /    Sodium channel protein type 11 subunit alpha

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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