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SLC12A2

DescriptionSolute carrier family 12 member 2

Gene and Protein Information

Gene ID6558
Uniprot Accession IDs P55011 Q8N713 Q8WWH7
Ensembl ID ENSP00000262461
Symbol NKCC1 BSC BSC2 NKCC1 PPP1R141
FamilyBelongs to the SLC12A transporter family.
Sequence
MEPRPTAPSSGAPGLAGVGETPSAAALAAARVELPGTAVPSVPEDAAPASRDGGGVRDEGPAAAGDGLGRPLGPTPSQSRFQVDLVSENAGRAAAAAAAAAAAAAAAGAGAGAKQTPADGEASGESEPAKGSEEAKGRFRVNFVDPAASSSAEDSLSDAAGVGVDGPNVSFQNGGDTVLSEGSSLHSGGGGGSGHHQHYYYDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKEPFEDGFANGEESTPTRDAVVTYTAESKGVVKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLESKKPKGFFGYKSEIFNENFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLNALQHSIRLSGVEDHVKNFRPQCLVMTGAPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEGLDISHLQGQEELLSSQEKSPGTKDVVVSVEYSKKSDLDTSKPLSEKPITHKVEEEDGKTATQPLLKKESKGPIVPLNVADQKLLEASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKENIIAFEEIIEPYRLHEDDKEQDIADKMKEDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLPPILLVRGNHQSVLTFYS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp471620SLC12A2solute carrier family 12 member 29598VGNC:8637OMA, EggNOG
Macaque704672SLC12A2solute carrier family 12 member 29544Inparanoid, OMA, EggNOG
Mouse20496Slc12a2solute carrier family 12, member 210090MGI:101924Inparanoid, OMA, EggNOG
Rat83629Slc12a2solute carrier family 12 member 210116RGD:620809Inparanoid, OMA, EggNOG
Dog481490SLC12A2solute carrier family 12 member 29615VGNC:46219Inparanoid, OMA, EggNOG
Horse100073036SLC12A2solute carrier family 12 member 29796VGNC:23020Inparanoid, OMA, EggNOG
Cow286845SLC12A2solute carrier family 12 member 29913VGNC:34665Inparanoid, OMA, EggNOG
Pig100516960SLC12A2solute carrier family 12 member 29823Inparanoid, OMA, EggNOG
Opossum100022720SLC12A2solute carrier family 12 member 213616Inparanoid, OMA, EggNOG
Chicken427123SLC12A2solute carrier family 12 member 29031CGNC:10891Inparanoid, OMA
Anole lizard100555453slc12a2solute carrier family 12 member 228377Inparanoid, OMA
Zebrafish415170slc12a2solute carrier family 12 (sodium/potassium/chloride transporter), member 27955Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC12 family of cation-coupled chloride transporters    /    Solute carrier family 12 member 2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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