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SLC6A4

DescriptionSodium-dependent serotonin transporter

Gene and Protein Information

Gene ID6532
Uniprot Accession IDs P31645 Q5EE02 SERT
Ensembl ID ENSP00000261707
Symbol HTT SERT HTT 5HTT OCD1 SERT 5-HTT SERT1 hSERT 5-HTTLPR
FamilyBelongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
Sequence
METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGTSSFICIPTYIAYRLIITPGTFKERIIKSITPETPTEIPCGDIRLNAV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp468201SLC6A4solute carrier family 6 member 49598VGNC:9626OMA, EggNOG
Macaque574140SLC6A4solute carrier family 6 member 49544Inparanoid, OMA, EggNOG
Mouse15567Slc6a4solute carrier family 6 (neurotransmitter transporter, serotonin), member 410090MGI:96285Inparanoid, OMA, EggNOG
Rat25553Slc6a4solute carrier family 6 member 410116RGD:3714Inparanoid, OMA, EggNOG
Dog491184SLC6A4solute carrier family 6 member 49615VGNC:46465Inparanoid, OMA, EggNOG
Horse100033848SLC6A4solute carrier family 6 member 49796VGNC:23261OMA, EggNOG
Cow282365SLC6A4solute carrier family 6 member 49913VGNC:49971Inparanoid, OMA, EggNOG
Pig100517307SLC6A4solute carrier family 6 member 49823OMA, EggNOG
Opossum100015330SLC6A4solute carrier family 6 member 413616Inparanoid, OMA, EggNOG
Chicken404747SLC6A4solute carrier family 6 member 49031CGNC:3120Inparanoid, OMA, EggNOG
Anole lizard100562250slc6a4solute carrier family 6 member 428377Inparanoid, OMA, EggNOG
Zebrafish664719slc6a4asolute carrier family 6 (neurotransmitter transporter), member 4a7955ZDB-GENE-060314-1Inparanoid, OMA
C. elegans171879mod-5Transporter6239Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    cation transporter    /    Sodium-dependent serotonin transporter
DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC6 neurotransmitter transporter family    /    Monoamine transporter subfamily    /    Sodium-dependent serotonin transporter

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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