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| Description | Sodium- and chloride-dependent GABA transporter 1 |
|---|
Gene and Protein Information
| Gene ID | 6529 |
|---|---|
| Uniprot Accession IDs | P30531 Q8N4K8 GAT-1 |
| Ensembl ID | ENSP00000287766 |
| Symbol | GABATR GABT1 GAT1 MAE GAT1 GABATR GABATHG |
| Family | Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily. |
| Sequence | MATNGSKVADGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPENGPEQPQAGSSTSKEAYI Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 460170 | SLC6A1 | solute carrier family 6 member 1 | 9598 | VGNC:8856 | OMA, EggNOG |
| Macaque | 696617 | SLC6A1 | solute carrier family 6 member 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 232333 | Slc6a1 | solute carrier family 6 (neurotransmitter transporter, GABA), member 1 | 10090 | MGI:95627 | Inparanoid, OMA, EggNOG |
| Rat | 79212 | Slc6a1 | solute carrier family 6 member 1 | 10116 | RGD:620533 | Inparanoid, OMA, EggNOG |
| Dog | 484655 | SLC6A1 | solute carrier family 6 member 1 | 9615 | VGNC:46453 | Inparanoid, OMA, EggNOG |
| Horse | 100051613 | SLC6A1 | solute carrier family 6 member 1 | 9796 | VGNC:23251 | Inparanoid, OMA, EggNOG |
| Cow | 407118 | SLC6A1 | solute carrier family 6 member 1 | 9913 | VGNC:34913 | Inparanoid, OMA, EggNOG |
| Pig | 100156668 | SLC6A1 | solute carrier family 6 member 1 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100015027 | SLC6A1 | solute carrier family 6 member 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 415960 | SLC6A1 | solute carrier family 6 member 1 | 9031 | CGNC:3654 | Inparanoid, OMA |
| Anole lizard | 100556107 | slc6a1 | solute carrier family 6 member 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | XB-GENE-5944458 | hypothetical protein LOC100127682 [Source:Xenbase;Acc:XB-GENE-5944458] | 8364 | OMA, EggNOG | ||
| Zebrafish | 492490 | slc6a1b | solute carrier family 6 (neurotransmitter transporter), member 1b | 7955 | ZDB-GENE-041114-57 | OMA, EggNOG |
| Zebrafish | 692318 | slc6a1a | solute carrier family 6 (neurotransmitter transporter), member 1a | 7955 | ZDB-GENE-060519-23 | Inparanoid, OMA |
| C. elegans | 191770 | snf-11 | Transporter | 6239 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / transporter / cation transporter / Sodium- and chloride-dependent GABA transporter 1
protein / transporter / cation transporter / Sodium- and chloride-dependent GABA transporter 1
DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC6 neurotransmitter transporter family / GABA transporter subfamily / Sodium- and chloride-dependent GABA transporter 1
protein / Transporter / SLC superfamily of solute carriers / SLC6 neurotransmitter transporter family / GABA transporter subfamily / Sodium- and chloride-dependent GABA transporter 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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