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TGFBR1

DescriptionTGF-beta receptor type-1

Gene and Protein Information

Gene ID7046
Uniprot Accession IDs P36897 Q6IR47 Q706C0 Q706C1 TGFR-1
Ensembl ID ENSP00000364133
Symbol ALK5 SKR4 AAT5 ALK5 ESS1 LDS1 MSSE SKR4 TBRI ALK-5 LDS1A LDS2A TBR-i TGFR-1 ACVRLK4 tbetaR-I
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence
MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTVKSSPGLGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp472992TGFBR1transforming growth factor beta receptor 19598VGNC:4876OMA, EggNOG
Macaque714952TGFBR1transforming growth factor beta receptor 19544Inparanoid, OMA, EggNOG
Mouse21812Tgfbr1transforming growth factor, beta receptor I10090MGI:98728Inparanoid, OMA, EggNOG
Rat29591Tgfbr1transforming growth factor, beta receptor 110116RGD:3852Inparanoid, EggNOG
Dog481628TGFBR1transforming growth factor beta receptor 19615VGNC:51764Inparanoid, OMA, EggNOG
Horse100034117TGFBR1transforming growth factor beta receptor 19796VGNC:49281Inparanoid, OMA, EggNOG
Cow282382TGFBR1transforming growth factor beta receptor 19913VGNC:35804Inparanoid, OMA, EggNOG
Opossum100011507TGFBR1transforming growth factor beta receptor 113616Inparanoid, OMA, EggNOG
PlatypusTGFBR1transforming growth factor beta receptor 1 [Source:HGNC Symbol;Acc:HGNC:11772]9258OMA, EggNOG
Anole lizard100566944tgfbr1transforming growth factor beta receptor 128377Inparanoid, OMA, EggNOG
Xenopus548715tgfbr1transforming growth factor beta receptor I8364XB-GENE-478587Inparanoid, OMA, EggNOG
Zebrafish792928tgfbr1btransforming growth factor, beta receptor 1 b7955ZDB-GENE-091027-1Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Tgf-beta receptor type-1
protein    /    receptor    /    TGF-beta receptor    /    Tgf-beta receptor type-1
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Tgf-beta receptor type-1
protein    /    receptor    /    protein kinase    /    Tgf-beta receptor type-1
protein    /    receptor    /    transferase    /    Tgf-beta receptor type-1
protein    /    receptor    /    kinase    /    Tgf-beta receptor type-1
DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    STKR family    /    STKR Type 1 subfamily    /    Tgf-beta receptor type-1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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