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TGFBR2

DescriptionTGF-beta receptor type-2

Gene and Protein Information

Gene ID7048
Uniprot Accession IDs P37173 B4DTV5 Q15580 Q6DKT6 Q99474 TGFR-2
Ensembl ID ENSP00000351905
Symbol AAT3 FAA3 LDS2 MFS2 RIIC LDS1B LDS2B TAAD2 TBRII TBR-ii TGFR-2 TGFbeta-RII
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence
MGRGLLRGLWPLHIVLWTRIASTIPPHVQKSVNNDMIVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNTSNPDLLLVIFQVTGISLLPPLGVAISVIIIFYCYRVNRQQKLSSTWETGKTRKLMEFSEHCAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSELEHLDRLSGRSCSEEKIPEDGSLNTTK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp460243TGFBR2transforming growth factor beta receptor 29598VGNC:9701OMA, EggNOG
Macaque703088TGFBR2transforming growth factor beta receptor 29544Inparanoid, OMA, EggNOG
Mouse21813Tgfbr2transforming growth factor, beta receptor II10090MGI:98729Inparanoid, OMA, EggNOG
Rat81810Tgfbr2transforming growth factor, beta receptor 210116RGD:69651Inparanoid, OMA, EggNOG
Dog477039TGFBR2transforming growth factor beta receptor 29615VGNC:47312Inparanoid, OMA, EggNOG
Horse100033860TGFBR2transforming growth factor beta receptor 29796VGNC:24056Inparanoid, OMA, EggNOG
Cow535376TGFBR2transforming growth factor beta receptor 29913VGNC:35805Inparanoid, OMA, EggNOG
Opossum100031897TGFBR2transforming growth factor beta receptor 213616Inparanoid, OMA, EggNOG
PlatypusTGFBR2transforming growth factor beta receptor 2 [Source:HGNC Symbol;Acc:HGNC:11773]9258OMA, EggNOG
Chicken396399TGFBR2transforming growth factor beta receptor 29031CGNC:8694Inparanoid, OMA, EggNOG
Anole lizard100552899tgfbr2transforming growth factor beta receptor 228377Inparanoid, OMA, EggNOG
Xenopus100488582tgfbr2transforming growth factor beta receptor II8364XB-GENE-485606Inparanoid, OMA, EggNOG
Zebrafish30739tgfbr2btransforming growth factor beta receptor 2b7955ZDB-GENE-980526-375OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Tgf-beta receptor type-2
protein    /    receptor    /    TGF-beta receptor    /    Tgf-beta receptor type-2
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Tgf-beta receptor type-2
protein    /    receptor    /    protein kinase    /    Tgf-beta receptor type-2
protein    /    receptor    /    transferase    /    Tgf-beta receptor type-2
protein    /    receptor    /    kinase    /    Tgf-beta receptor type-2
DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    STKR family    /    STKR Type 2 subfamily    /    Tgf-beta receptor type-2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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