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MPL

DescriptionThrombopoietin receptor

Gene and Protein Information

Gene ID4352
Uniprot Accession IDs P40238 Q5JUZ0 TPO-R
Ensembl ID ENSP00000361548
Symbol TPOR MPLV TPOR C-MPL CD110 THPOR THCYT2
FamilyBelongs to the type I cytokine receptor family. Type 1 subfamily.
Sequence
MPSWALFMVTSCLLLAPQNLAQVSSQDVSLLASDSEPLKCFSRTFEDLTCFWDEEEAAPSGTYQLLYAYPREKPRACPLSSQSMPHFGTRYVCQFPDQEEVRLFFPLHLWVKNVFLNQTRTQRVLFVDSVGLPAPPSIIKAMGGSQPGELQISWEEPAPEISDFLRYELRYGPRDPKNSTGPTVIQLIATETCCPALQRPHSASALDQSPCAQPTMPWQDGPKQTSPSREASALTAEGGSCLISGLQPGNSYWLQLRSEPDGISLGGSWGSWSLPVTVDLPGDAVALGLQCFTLDLKNVTCQWQQQDHASSQGFFYHSRARCCPRDRYPIWENCEEEEKTNPGLQTPQFSRCHFKSRNDSIIHILVEVTTAPGTVHSYLGSPFWIHQAVRLPTPNLHWREISSGHLELEWQHPSSWAAQETCYQLRYTGEGHQDWKVLEPPLGARGGTLELRPRSRYRLQLRARLNGPTYQGPWSSWSDPTRVETATETAWISLVTALHLVLGLSAVLGLLLLRWQFPAHYRRLRHALWPSLPDLHRVLGQYLRDTAALSPPKATVSDTCEEVEPSLLEILPKSSERTPLPLCSSQAQMDYRRLQPSCLGTMPLSVCPPMAESGSCCTTHIANHSYLPLSYWQQP
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque723813MPLMPL proto-oncogene, thrombopoietin receptor9544OMA, EggNOG
Mouse17480Mplmyeloproliferative leukemia virus oncogene10090MGI:97076Inparanoid, OMA, EggNOG
Rat366455MplMPL proto-oncogene, thrombopoietin receptor10116RGD:1311069Inparanoid, OMA, EggNOG
Dog610801MPLMPL proto-oncogene, thrombopoietin receptor9615VGNC:43338Inparanoid, OMA, EggNOG
Horse100066544MPLMPL proto-oncogene, thrombopoietin receptor9796VGNC:20287Inparanoid, OMA, EggNOG
Cow528492MPLMPL proto-oncogene, thrombopoietin receptor9913VGNC:31578Inparanoid, OMA, EggNOG
Pig100626347MPLMPL proto-oncogene, thrombopoietin receptor9823Inparanoid, EggNOG
Chicken414804MPLMPL proto-oncogene, thrombopoietin receptor9031CGNC:7572Inparanoid, OMA
Zebrafish445381mplMPL proto-oncogene, thrombopoietin receptor7955ZDB-GENE-060421-1Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    type I cytokine receptor    /    Thrombopoietin receptor
DTO Classes
protein    /    Receptor    /    Cytokine receptor    /    Type I cytokine receptor    /    Thrombopoietin receptor

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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