SIGLEC8

DescriptionSialic acid-binding Ig-like lectin 8

Gene and Protein Information

Gene ID27181
Uniprot Accession IDs Q9NYZ4 Q7Z728 Siglec-8
Ensembl ID ENSP00000321077
Symbol SAF2 SAF2 SIGLEC-8 SIGLEC8L
FamilyBelongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Sequence
MLLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSDPVHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKGSYFFRLERGSMKWSYKSQLNYKTKQLSVFVTALTHRPDILILGTLESGHSRNLTCSVPWACKQGTPPMISWIGASVSSPGPTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLRLVCAVNSNPPARLSWTRGSLTLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSLSLQNEGTGTSRPVSQVTLAAVGGAGATALAFLSFCIIFIIVRSCRKKSARPAAGVGDTGMEDAKAIRGSASQGPLTESWKDGNPLKKPPPAVAPSSGEEGELHYATLSFHKVKPQDPQGQEATDSEYSEIKIHKRETAETQACLRNHNPSSKEVRG
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp107966154SIGLEC8sialic acid binding Ig like lectin 89598VGNC:13310Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    immunoglobulin superfamily cell adhesion molecule    /    Sialic acid-binding Ig-like lectin 8
protein    /    receptor    /    immunoglobulin receptor superfamily    /    Sialic acid-binding Ig-like lectin 8
protein    /    receptor    /    cytokine receptor    /    Sialic acid-binding Ig-like lectin 8
protein    /    receptor    /    defense/immunity protein    /    Sialic acid-binding Ig-like lectin 8
protein    /    receptor    /    membrane-bound signaling molecule    /    Sialic acid-binding Ig-like lectin 8
protein    /    receptor    /    myelin protein    /    Sialic acid-binding Ig-like lectin 8
DTO Classes
protein    /    Receptor    /    Cytokine receptor    /    Immunoglobulin receptor superfamily    /    Sialic acid-binding Ig-like lectin 8

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

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