Tebipenem - 10mM in DMSO , CAS No.161715-21-5

CAS: 161715-21-5 Cat. No.: T655272 Molecular Weight: 383.5 PubChem CID: 9800194

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Tebipenem is an orally available carbapenem antibiotic , shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa .

In Vitro

Tebipenem exhibits slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin, and apparent K m and k cat values of 0.8 μM and 0.03 min -1 , respectively. Tebipenem shows potent activity against B. pseudomallei , with MIC 50 and MIC 90 values of both 2 mg/L. Tebipenem shows good activity against S. pneumoniae , with the MIC range of ≤0.25 μg/mL in all of the S. pneumoniae isolates. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:β-lactam

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Tebipenem is an orally available carbapenem antibiotic , shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa .

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1SC3CN(C3)C4=NCCS4)C(=O)O)[C@@H](C)O
• Alternate CAS: 161715-21-5
• PubChem CID: 9800194
• MeSH Entry Terms: SPR994;tebipenem
• Molecular Weight: 383.5