Tetraglycol - UltraBio™, Ultra pure , CAS No.31692-85-0

CAS: 31692-85-0 Cat. No.: T432615 EC Number: 608-659-1

GRADE & PURITY UltraBio™, Ultra pure

Synonyms

Glycofurol | Tetrahydrofurfuryl polyethylene glycol ether | Tetrahydrofurfuryl alcohol polyethyleneglycol ethe

Storage

Room temperature

Overview

Efficient solubilizer for glibenclamide (GBD)

Specifications

Synonyms

Glycofurol | Tetrahydrofurfuryl polyethylene glycol ether | Tetrahydrofurfuryl alcohol polyethyleneglycol ethe

Specifications & Purity

UltraBio™, Ultra pure

Biochemical and Physiological Mechanisms

Liquid glycofurol can readily transform into gel systems with excellent elasticity due to which, it can be used as a medium to dissolve water-insoluble drugs.

Storage

Room temperature

Grade

Ultra pure, UltraBio™

Note

Note: Do not confuse with tetraglycol, sometimes referred to as tetraglycol.

Names and Identifiers

• Canonical Smiles: C1CC(OC1)COCCO
• IUPAC Name: 2-(oxolan-2-ylmethoxy)ethanol
• InChIKey: CTPDSKVQLSDPLC-UHFFFAOYSA-N
• INCHI: 1S/C7H14O3/c8-3-5-9-6-7-2-1-4-10-7/h7-8H,1-6H2
• Isomeric SMILES: C1CC(OC1)COCCO
• WGK Germany: 3
• RTECS: MD0907500

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Tetrahydrofurans

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Tetrahydrofurans
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Tetrahydrofurans
• Alternative Parents: Oxacyclic compounds Dialkyl ethers Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Tetrahydrofuran - Oxacycle - Ether - Dialkyl ether - Organic oxygen compound - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Alcohol - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as tetrahydrofurans. These are heterocyclic compounds containing a saturated, aliphatic, five-membered ring where a carbon is replaced by an oxygen.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Refractive Index: 1.462
• Specific Rotation[α]: +0.4°（C=0.5，methanol）
• Flash Point(°F): 275.0 °F
• Flash Point(°C): 135 °C
• Melt Point(°C): ≤ -100 °C
• Molecular Weight: 146.180 g/mol
• XLogP3: -0.200
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 146.094 Da
• Monoisotopic Mass: 146.094 Da
• Topological Polar Surface Area: 38.700 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 84.900
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Liheng Feng, Lixia Guo, Xiaoju Wang.  (2016)  Preparation, properties and applications in cell imaging and ions detection of conjugated polymer nanoparticles with alcoxyl bonding fluorene core.  BIOSENSORS & BIOELECTRONICS,      [PMID:27598853] [10.1016/j.bios.2016.08.114]

2. Yong Hou, Shoupeng Cao, Xueming Li, Beibei Wang, Yuxin Pei, Lin Wang, Zhichao Pei.  (2014)  One-Step Synthesis of Dual Clickable Nanospheres via Ultrasonic-Assisted Click Polymerization for Biological Applications.  ACS Applied Materials & Interfaces,      [PMID:25211060] [10.1021/am504479w]