Thalidomide 4'-ether-alkylC5-acid - ≥95%(HPLC) , CAS No.2087490-48-8

CAS: 2087490-48-8 Cat. No.: T288669 Molecular Weight: 388.38 EC Number: 187-553-2 PubChem CID: 132212109

GRADE & PURITY ≥95%(HPLC)

Synonyms

6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]hexanoic acid | Thalidomide-O-C5-acid

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Application

230

Specifications

Synonyms

6-[[2-(2, 6-Dioxo-3-piperidinyl)-2, 3-dihydro-1, 3-dioxo-1H-isoindol-4-yl]oxy]hexanoic acid | Thalidomide-O-C5-acid

Specifications & Purity

≥95%(HPLC)

Biochemical and Physiological Mechanisms

Functionalized cereblon ligand for PROTAC®research and development; incorporates an E3 ligase ligand plus an alkylC5 linker with a terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%(HPLC)

Names and Identifiers

• Canonical Smiles: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCCCCCC(=O)O
• IUPAC Name: 6-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyhexanoic acid
• InChIKey: PBZGPWVWKSADLD-UHFFFAOYSA-N
• INCHI: 1S/C19H20N2O7/c22-14-9-8-12(17(25)20-14)21-18(26)11-5-4-6-13(16(11)19(21)27)28-10-3-1-2-7-15(23)24/h4-6,12H,1-3,7-10H2,(H,23,24)(H,20,22,25)
• PubChem CID: 132212109
• Molecular Weight: 388.38