Thalidomide-O-amido-C8-NH2 hydrochloride - ≥95%(HPLC) , CAS No.2415263-07-7

CAS: 2415263-07-7 Cat. No.: T287178 Molecular Weight: 494.97 PubChem CID: 146018961

GRADE & PURITY ≥95%(HPLC)

Synonyms

N-(8-Aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-acetamide hydrochloride

Storage

Room temperature,Desiccated

Shipped In

Normal

Overview

Thalidomide-O-amido-C8-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs。

Specifications

Synonyms

N-(8-Aminooctyl)-2-[[2-(2, 6-dioxo-3-piperidinyl)-2, 3-dihydro-1, 3-dioxo-1H-isoindol-4-yl]oxy]-acetamide hydrochloride

Specifications & Purity

≥95%(HPLC)

Biochemical and Physiological Mechanisms

Functionalized cereblon ligand for PROTAC®research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R

Storage

Room temperature, Desiccated

Shipped In

Normal

Purity

≥95%(HPLC)

Names and Identifiers

• Pubchem Sid: 504773615
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773615
• Canonical Smiles: NCCCCCCCCNC(COC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O.Cl
• InChIKey: KPPZEDZTBDIUJN-UHFFFAOYNA-N
• PubChem CID: 146018961
• Molecular Weight: 494.97