α-Thujone - Moligand™, 10 mM in DMSO , CAS No.546-80-5

CAS: 546-80-5 Cat. No.: T1495377 Formula: C₁₀H₁₆O Molecular Weight: 152.23 EC Number: 208-912-2

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC 50 for α-Thujone is 21 μM in suppressing the GABA -induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy . α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

ACTIVATOR

Names and Identifiers

• Isomeric SMILES: C[C@@H]1[C@H]2C[C@]2(CC1=O)C(C)C
• WGK Germany: 3
• RTECS: XO9625000
• Molecular Weight: 152.23

Chemical and Physical Properties

• Refractive Index: n20/D 1.450
• Specific Rotation[α]: α20/D -19°±2.0° neat
• Flash Point(°F): 147.2 °F
• Flash Point(°C): 64 °C

References

1. Chongshan Yang, Dandan Duan, Chunwang Dong, Chuanxia Li, Guanglin Li, Yunhai Zhou, Yifan Gu, Yachao Liu, Chunjiang Zhao, Daming Dong.  (2023)  Detection of volatile organic compounds in adulterated tea using Fourier transform infrared spectroscopy and Proton-transfer-reaction mass spectrometry.  FOOD CHEMISTRY,      [PMID:37182490] [10.1016/j.foodchem.2023.136308]