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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 34 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Thymidine (Deoxythymidine, 2'-Deoxythymidine, 5-Methyldeoxyuridine, DThyd, NSC 21548) is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. As a constituent of DNA, thymidine pairs with adenine in th
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| Isomeric SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O |
|---|---|
| WGK Germany | 3 |
| RTECS | XP2071000 |
| Molecular Weight | 242.23 |
| Beilstein | 89285 |
| Reaxy-Rn | 889638 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=889638&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
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View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Specific Rotation[α] | 33 ° (C=1, 1mol/L NaOH) |
|---|---|
| Melt Point(°C) | 183-191°C |
| 1. Yating Li, Jason Tan, Yanqin Tu, Jingnan Wu, Zaifang Zhang, Yifeng Wei, Xinan Jiao, Yan Zhou. (2025) Distinct Phage-Encoded Enzymes for Substitution of Deoxythymidine by Deoxyuridine in Phage Genomes. Advanced Science, [PMID:41001765] [10.1002/advs.202512937] |
| 2. Yansheng Liu, Haoteng Wang, Guofu Wang, Xiaobo Jia, Jin Zhou, Hongqi Li, Haixin Chang, Zhicheng Jin, Kang Li, Zhaoxu Li. (2025) Real-time detection of mercury ions in environmental water conditions by using a differential phase SPR system equipped with a repeatable SPR chip. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.115312] |
| 3. Xu Lian, Li Hui-Min, Lin Juan. (2023) Efficient synthesis of 2’-deoxyguanosine in one-pot cascade by employing an engineered purine nucleoside phosphorylase from Brevibacterium acetylicum. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 39 (10): (1-9). [PMID:37606812] [10.1007/s11274-023-03721-1] |
| 4. Fei Wang, Fan Yang, Jiawei Liu, Quan Bai. (2023) Studies on the retention mechanism of solutes in hydrophilic interaction chromatography using stoichiometric displacement theory II. HILIC/RPLC dual-retention mechanism of solutes in hydrophilic interaction chromatography over the entire range of water concentration in mobile phase. TALANTA, [PMID:37385194] [10.1016/j.talanta.2023.124858] |
| 5. Ye Shu, Tong Chen, Tao Liu, Hechen Xu, Jinjin He, Zhihui Cai, Wanning Zhu, Zihan Zhao, Jun Jiang. (2023) Preparation and characterization of mixed-mode hydrophilic stationary phase based on triple hydrophilic functionalized moieties and its application to traditional Chinese herbal compound. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2023.108863] |
| 6. Li Gao, Yuan Wang, Yaqiong Qin, Yaming Sun, Lijun He, Shusheng Zhang, Wenjie Zhao. (2023) Preparation and characterization of glucose-based covalent organic polymer coated silica as stationary phase for high-performance liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, [PMID:36857980] [10.1016/j.chroma.2023.463876] |
| 7. Kaixing Luo, Yu Luo, Yanjuan Liu, Yuefei Zhang, Wei Chen, Zhengwu Bai, Sheng Tang. (2022) Hydrophobic and hydrophilic selectivity of a multifunctional carbonyldiimidazolium/dodecyl modified silica stationary phase. JOURNAL OF CHROMATOGRAPHY A, [PMID:35810643] [10.1016/j.chroma.2022.463300] |
| 8. Zhihua Song, Jinqiu Liu, Deyang Zhang, Yumeng Wang, Wen Lin, Yi Bi, Hongbo Wang, Maryam Arabi, Jinhua Li, Jiping Ma, Yan Wang, Lingxin Chen. (2022) Synthesis of C8F13-SiO2 stationary phase for chromatographic separation of highly polar compounds. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2022.107670] |
| 9. Yan Wu, Kaixing Luo, Yanjuan Liu, Wei Chen, Zhengwu Bai, Sheng Tang. (2022) Innovative preparation of ureido/dodecyl dual-functionalized silica as a versatile mixed-mode stationary phase for high-resolution chromatographic separations. JOURNAL OF CHROMATOGRAPHY A, [PMID:35085896] [10.1016/j.chroma.2022.462834] |
| 10. Chao Fan, Bei Liu, Hui Li, Kaijun Quan, Jia Chen, Hongdeng Qiu. (2021) N-Vinyl pyrrolidone and undecylenic acid copolymerized on silica surface as mixed-mode stationary phases for reversed-phase and hydrophilic interaction chromatography. JOURNAL OF CHROMATOGRAPHY A, [PMID:34509123] [10.1016/j.chroma.2021.462534] |
| 11. Jia Ding, Fei Liu, Chunling Qi, Yunlei Zhou, Huanshun Yin, Shiyun Ai. (2021) Enhanced photoactivity of perovskite Bi4NbO8Cl/PTC-NH2 heterojunction and its application for photoelectrochemical sensing of DNA hydroxymethylation. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2021.130211] |
| 12. Qian Wang, Huanshun Yin, Yunlei Zhou, Jun Wang, Shiyun Ai. (2021) Photoelectrochemical biosensor for 5-formylcytosine deoxyribonucleoside detection based on BiIO4-WS2/CuO ternary heterojunction. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2021.130019] |
| 13. Tong Chen, Liang Xu, Guangsan Song, Yuan Li, Hong Xu, Hongbin Zhou, Zhen Xiao, Ping Li. (2021) Preparation and application of Au nanoparticles-decorated SO3H-cofunctionalized silica stationary phase for per aqueous liquid chromatography. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2021.105985] |
| 14. Chao Fan, Hao Tang, Licheng Wang, Yijing Li, Xusheng Wang, Shuai Wang, Xiaojing Liang. (2020) The preparation of a core–shell stationary phase by the in situ polymerization of a hydrophilic polymer on the surface of silica and its chromatographic performance. NEW JOURNAL OF CHEMISTRY, 44 (27): (11704-11709). [PMID:] [10.1039/D0NJ01197E] |
| 15. Zhonghua Dong, Yueyue Sun, Guangwei Wei, Siying Li, Zhongxi Zhao. (2019) A Nucleoside/Nucleobase-Rich Extract from Cordyceps Sinensis Inhibits the Epithelial–Mesenchymal Transition and Protects against Renal Fibrosis in Diabetic Nephropathy. MOLECULES, 24 (22): (4119). [PMID:31739543] [10.3390/molecules24224119] |
| 16. Tianpei Cai, Haijuan Zhang, Jia Chen, Zhan Li, Hongdeng Qiu. (2019) Polyethyleneimine-functionalized carbon dots and their precursor co-immobilized on silica for hydrophilic interaction chromatography. JOURNAL OF CHROMATOGRAPHY A, [PMID:30922720] [10.1016/j.chroma.2019.03.026] |
| 17. Tengda Wang, Jianxing Shan, Li Wang, Xiangwen Zhang, Guozhu Li. (2019) On the kinetics of catalytic hydrogenation over Pd nanoparticles regulated by various nucleosides. CHEMICAL ENGINEERING SCIENCE, [PMID:] [10.1016/j.ces.2019.02.014] |
| 18. Cai Tianpei, Zhang Haijuan, Rahman A. F. M. Mustafizur, Shi Yan-Ping, Qiu Hongdeng. (2017) Silica grafted with silanized carbon dots as a nano-on-micro packing material with enhanced hydrophilic selectivity. MICROCHIMICA ACTA, 184 (8): (2629-2636). [PMID:] [10.1007/s00604-017-2277-1] |
| 19. Chaozhan Wang, Huanhuan Xu, Yinmao Wei. (2015) The preparation of high-capacity boronate affinity adsorbents by surface initiated reversible addition fragmentation chain transfer polymerization for the enrichment of ribonucleosides in serum. ANALYTICA CHIMICA ACTA, [PMID:26703260] [10.1016/j.aca.2015.11.013] |
| 20. Qing Wang, Yao Long, Lin Yao, Li Xu, Zhi-Guo Shi, Lanying Xu. (2015) Preparation, characterization and application of a reversed phase liquid chromatography/hydrophilic interaction chromatography mixed-mode C18-DTT stationary phase. TALANTA, [PMID:26695288] [10.1016/j.talanta.2015.09.009] |
| 21. Wang Xue-Jie, You Jin-Zong. (2015) Study on the molecular structure and thermal stability of pyrimidine nucleoside analogs. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 120 (1): (1009-1025). [PMID:] [10.1007/s10973-014-4362-6] |
| 22. Yali Yang, Jia Chen, Xiaojing Liang, Bei Liu, Kaijun Quan, Xiuhui Liu, Hongdeng Qiu. (2024) Adjustable chromatographic performance of silica-based mixed-mode stationary phase through the control of co-grafting amounts of imidazole and C18 chain. JOURNAL OF CHROMATOGRAPHY A, [PMID:38598894] [10.1016/j.chroma.2024.464889] |
| 23. Min Zhang, Dandan Guo, Yan Zhu, Shaohua Huang. (2025) Controllable preparation and application of mixed-mode stationary phases based on green peptide coupling reactions. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.113347] |
| 24. Xingkang Diao, GuoHua Qi, Xinli Li, Yu Tian, Jing Li, Yongdong Jin. (2025) Label-Free Exosomal SERS Detection Assisted by Machine Learning for Accurately Discriminating Cell Cycle Stages and Revealing the Molecular Mechanisms during the Mitotic Process. ANALYTICAL CHEMISTRY, [PMID:39999424] [10.1021/acs.analchem.4c06240] |
| 25. Jinlei Yang, Jing Wang, Runsong Cheng, Tianyi Liao, Siyuan Pan, Murong Du, Weiliang Liu, Liying Yan, Sichun Zhang, Xinrong Zhang. (2025) Microseparation of Lipophilic and Hydrophilic Metabolites for Single Oocyte Mass Spectrometry Analysis. ANALYTICAL CHEMISTRY, [PMID:39800910] [10.1021/acs.analchem.4c04900] |
| 26. Tong Ren, Zhen Feng, Fang Jiang, Xingtong Liu, Tingting Chen, Yanli Guo, Lei Tian, Xiao-Feng Kang, Fujun Yao. (2024) Nanopore detection of guanine derivatives based on vacancy G-quadruplex DNA. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.112366] |
| 27. Xingyun Zhao, Yifan Niu, Chengxiao Zhao, Zhenyu Li, Ke Li, Xuemei Qin. (2024) Simplified Synthesis of Poly(ethyleneimine)-Modified Silica Particles and Their Application in Oligosaccharide Isolation Methods. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25 (17): (9465). [PMID:39273411] [10.3390/ijms25179465] |
| 28. Chunyan Liu, Yanjuan Liu, Yuefei Zhang, Wei Chen, Sheng Tang. (2024) Synergistic expression of ZIF-67 and amphiphilic polymer hydrogel in multi-mode liquid chromatographic separation. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2024.127827] |
| 29. Li Hengye, Zhang Xuemeng, Zhang Lin, Cang Hui, Kong Fenying, Fan Dahe, Wang Wei. (2018) Hyperbranched Polyglycerol Functionalized Silica Stationary Phase for Hydrophilic Interaction Liquid Chromatography. ANALYTICAL SCIENCES, 34 (4): (433-438). [PMID:29643306] [10.2116/analsci.17P486] |
| 30. Hengye Li, Xuemeng Zhang, Lin Zhang, Xiaojin Wang, Fenying Kong, Dahe Fan, Lei Li, Wei Wang. (2016) Preparation of a boronate affinity silica stationary phase with enhanced binding properties towards cis-diol compounds. JOURNAL OF CHROMATOGRAPHY A, [PMID:27776772] [10.1016/j.chroma.2016.10.050] |
| 31. Qing Wang, Mao Ye, Li Xu, Zhi-guo Shi. (2015) A reversed-phase/hydrophilic interaction mixed-mode C18-Diol stationary phase for multiple applications. ANALYTICA CHIMICA ACTA, [PMID:26320974] [10.1016/j.aca.2015.06.058] |
| 32. Jianbo Zhang, Yidong Zhong, Yue Feng, Meijun Chen. (2025) Nano-dendritic PdPtCu alloys for efficient dye degradation through plasmon-enhanced Fenton-like reaction. JOURNAL OF ALLOYS AND COMPOUNDS, [PMID:] [10.1016/j.jallcom.2025.184427] |
| 33. Chen Jiajing, Lin Juan, Ouyang Dan, Lin Zian. (2025) Hydroxyl-Functionalized Covalent Organic Framework Assisted Laser Desorption/Ionization Mass Spectrometry-Based Direct Serum Metabolic Profiling for Gout Screening. Journal of Analysis and Testing, [PMID:] [10.1007/s41664-025-00403-9] |
| 34. Yu Jinzhi, Wang Naixuan, Liu Lijun, Zhou Hong, Zhang Anying, Wang Xinyan. (2026) Grass carp S100A10a/10b, two skin wound-induced genes, augment epithelial cell proliferation and migration in vitro. FISH PHYSIOLOGY AND BIOCHEMISTRY, 52 (1): (11). [PMID:41498859] [10.1007/s10695-025-01632-6] |
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