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TMEA(tris(2-maleimidoethyl)amine) , CAS No.T639047
AVAILABLE TO ORDER
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Product introduction：
TMEA is a trifunctional crosslinker containing three reactive maleimide groups to enable three-way conjugation and polymerization of sulfhydryl-containing molecules.
• Reactive groups:maleimide (on three termini)
• Reactive towards: sulfhydryl groups
• 3-way, sulfhydryl-to-sulfhydryl crosslinker; tris (2-maleimidoethyl) amine, composed of three maleimide groups on short spacer arms
• Water-insoluble—dissolve first in DMF or DMSO, then add to aqueous reaction buffers
• Noncleavable
• Useful for the preparation of trimeric complexes of cysteine-containing peptides and other sulfhydryl-containing compounds
• Core molecule for the construction of dendritic polymers
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
• Reactive Moiety:Maleimide
• Crosslinker Type:Homotrifunctional
• Form:Solid
• Spacer:Medium(10 to 30 Å)
• Labeling Method:Chemical Labeling
• Spacer Arm Length:10.3 Å
• Reactive groups:maleimide (on three termini)
• Reactive towards: sulfhydryl groups
• 3-way, sulfhydryl-to-sulfhydryl crosslinker; tris (2-maleimidoethyl) amine, composed of three maleimide groups on short spacer arms
• Water-insoluble—dissolve first in DMF or DMSO, then add to aqueous reaction buffers
• Noncleavable
• Useful for the preparation of trimeric complexes of cysteine-containing peptides and other sulfhydryl-containing compounds
• Core molecule for the construction of dendritic polymers
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
• Reactive Moiety:Maleimide
• Crosslinker Type:Homotrifunctional
• Form:Solid
• Spacer:Medium(10 to 30 Å)
• Labeling Method:Chemical Labeling
• Spacer Arm Length:10.3 Å
Specifications
Storage
Store at 2-8°C, Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Properties
| Reactivity | Sulfhydryl-Sulfhydryl |
|---|
Names and Identifiers
| Molecular Weight | 386.36 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | DMF,DMSO |
|---|
Solution Calculators
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Customer Reviews
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