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· · COA & SDS available for every product · Same-day shipping on in-stock items Tozadenant - Moligand™, ≥98% , Adenosine A2a receptor antagonist, CAS No.870070-55-6, Adenosine A2a receptor antagonist
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
4-Hydroxy-N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-4-methylpiperidine-1-carboxamide | A2A | A862938 | PB19761 | Tozadenant [USAN:INN] | MFCD21642026 | Ro-4494351-002 | RO4494351-002 | VJB07055 | AKOS000206566 | Hyosceine | SYN115 | SYN-115 | A2A-(3)
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Tozadenant is an adenosine A2A receptor antagonist, with Ki of 11.5 nM on human A2A and 6 nM on rhesus A2A.
Specifications Synonyms
4-Hydroxy-N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-4-methylpiperidine-1-carboxamide | A2A | A862938 | PB19761 | Tozadenant [USAN:INN] | MFCD21642026 | Ro-4494351-002 | RO4494351-002 | VJB07055 | AKOS000206566 | Hyosceine | SYN115 | SYN-115 | A2A-(3)
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
Tozadenant (SYN-115) is an adenosine A2a receptor antagonist. Treatment of Parkinson's disease, dopaminergic neurotransmission disorders. Tozadenant (SYN-115) is useful for treatment of post-traumatic stress disorder.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Adenosine A2a receptor antagonist
Product Properties Names and Identifiers Canonical Smiles CC1(CCN(CC1)C(=O)NC2=NC3=C(C=CC(=C3S2)N4CCOCC4)OC)O IUPAC Name 4-hydroxy-N-(4-methoxy-7-morpholin-4-yl-1,3-benzothiazol-2-yl)-4-methylpiperidine-1-carboxamide InChIKey XNBRWUQWSKXMPW-UHFFFAOYSA-N INCHI 1S/C19H26N4O4S/c1-19(25)5-7-23(8-6-19)18(24)21-17-20-15-14(26-2)4-3-13(16(15)28-17)22-9-11-27-12-10-22/h3-4,25H,5-12H2,1-2H3,(H,20,21,24) Isomeric SMILES CC1(CCN(CC1)C(=O)NC2=NC3=C(C=CC(=C3S2)N4CCOCC4)OC)O PubChem CID 11618368 Molecular Weight 406.50
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Benzothiazoles Subclass Not available Intermediate Tree Nodes Not available Direct Parent Benzothiazoles Alternative Parents Methoxyanilines Piperidinecarboxamides Anisoles Dialkylarylamines Alkyl aryl ethers Morpholines Tertiary alcohols Heteroaromatic compounds Thiazoles Ureas Oxacyclic compounds Dialkyl ethers Azacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds Molecular Framework Aromatic heteropolycyclic compounds Substituents 1,3-benzothiazole - 1-piperidinecarboxamide - Piperidinecarboxamide - Methoxyaniline - Anisole - Phenol ether - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Alkyl aryl ether - Benzenoid - Piperidine - Oxazinane - Morpholine - Heteroaromatic compound - Thiazole - Tertiary alcohol - Azole - Urea - Tertiary amine - Oxacycle - Azacycle - Dialkyl ether - Ether - Alcohol - Organonitrogen compound - Organooxygen compound - Carbonyl group - Organic nitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Amine - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as benzothiazoles. These are organic compounds containing a benzene fused to a thiazole ring (a five-membered ring with four carbon atoms, one nitrogen atom and one sulfur atom). External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility DMSO Molecular Weight 406.500 g/mol XLogP3 1.700 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 3 Exact Mass 406.167 Da Monoisotopic Mass 406.167 Da Topological Polar Surface Area 115.000 Ų Heavy Atom Count 28 Formal Charge 0 Complexity 554.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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