Tris(hydroxymethyl)aminomethane acetate salt - ≥99% , CAS No.6850-28-8

CAS: 6850-28-8 Cat. No.: T113199 Molecular Weight: 181.19 Beilstein Registry Number: 3702918 EC Number: 229-939-6 PubChem CID: 16218782

GRADE & PURITY ≥99%

Synonyms

1,3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-, ACETATE | Tris acetate | AS-15233 | tris-(hydroxymethyl) aminomethane acetate | A051F48W36 | acetic acid;2-amino-2-(hydroxymethyl)propane-1,3-diol | Trizma acetate | W-104667 | 2-Amino-2-(hydroxymethyl)-1,3-pro

Storage

Room temperature

Shipped In

Normal

Overview

Trometamol acetate (Tromethamine acetate) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol acetate is an effective amine compound for pH control in the physiological range.

Specifications

Synonyms

1, 3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-, ACETATE | Tris acetate | AS-15233 | tris-(hydroxymethyl) aminomethane acetate | A051F48W36 | acetic acid;2-amino-2-(hydroxymethyl)propane-1, 3-diol | Trizma acetate | W-104667 | 2-Amino-2-(hydroxymethyl)-1, 3-pro

Specifications & Purity

≥99%

Storage

Room temperature

Shipped In

Normal

Purity

≥99%

Names and Identifiers

• Canonical Smiles: CC(=O)O.C(C(CO)(CO)N)O
• IUPAC Name: acetic acid;2-amino-2-(hydroxymethyl)propane-1,3-diol
• InChIKey: PIEPQKCYPFFYMG-UHFFFAOYSA-N
• INCHI: 1S/C4H11NO3.C2H4O2/c5-4(1-6,2-7)3-8;1-2(3)4/h6-8H,1-3,5H2;1H3,(H,3,4)
• Isomeric SMILES: CC(=O)O.C(C(CO)(CO)N)O
• WGK Germany: 3
• PubChem CID: 16218782
• Molecular Weight: 181.19
• Beilstein: 3702918

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Class Organonitrogen compounds
      • Subclass Amines
        • Level5 Alkanolamines
          • Level6 1,2-aminoalcohols

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Class: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Alkanolamines
• Direct Parent: 1,2-aminoalcohols
• Alternative Parents: Monocarboxylic acids and derivatives Carboxylic acids Primary alcohols Organopnictogen compounds Organic zwitterions Organic salts Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Not available
• Substituents: 1,2-aminoalcohol - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organic oxygen compound - Organic salt - Organic zwitterion - Primary amine - Primary alcohol - Organooxygen compound - Hydrocarbon derivative - Primary aliphatic amine - Organic oxide - Organopnictogen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as 1,2-aminoalcohols. These are organic compounds containing an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom.
• External Descriptors: acetate salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water
• Melt Point(°C): 123°C
• Molecular Weight: 181.190 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 181.095 Da
• Monoisotopic Mass: 181.095 Da
• Topological Polar Surface Area: 124.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 85.100
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

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2. Jiangxiong Zhu, Hao Yin, Yang Wang, Lumei Wang, Xueqing Geng, Yun Deng.  (2024)  Conformational change-based fluorometric aptasensor for sensitive cadmium(II) detection in fruits and vegetables.  Analytical Methods,      [PMID:39143932] [10.1039/D4AY01333F]

3. Yuhan He, Haien Fan, Jianxiu Wang, Hailin Tang, Xinyao Yi.  (2026)  Construction of ratiometric nano-converter based on DNA-templated silver nanocluster for piRNA sensing.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2026.139470]