Tylosin tartrate - potency: ≥800 units/mg tylosin , CAS No.74610-55-2

CAS: 74610-55-2 Cat. No.: T118611 EC Number: 616-119-1

GRADE & PURITY potency: ≥800 units/mg tylosin

Synonyms

s3162 | TYLOSIN TARTRATE [USP MONOGRAPH] | Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1) | Tylosin tartrate (USP) | Tylosin (tartrate) | NSC 758961 | Tylan injectable | EINECS 215-781-5 | DTXSID3045938 | Tylosin tartrate, potency: >=800 units/mg tylosi

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Synonyms

s3162 | TYLOSIN TARTRATE [USP MONOGRAPH] | Tylosin, (2R, 3R)-2, 3-dihydroxybutanedioate (1:1) | Tylosin tartrate (USP) | Tylosin (tartrate) | NSC 758961 | Tylan injectable | EINECS 215-781-5 | DTXSID3045938 | Tylosin tartrate, potency: >=800 units/mg tylosi

Specifications & Purity

potency: ≥800 units/mg tylosin

Biochemical and Physiological Mechanisms

Broad spectrum macrocyclic lactone antibiotic. Protein synthesis inhibitor. Binds to the 50S subunit of the bacterial ribosome. Shows bacteriostatic effects in vivo. Orally active.

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Names and Identifiers

• Canonical Smiles: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC
• IUPAC Name: (2R,3R)-2,3-dihydroxybutanedioic acid;2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
• InChIKey: ICVKYYINQHWDLM-KBEWXLTPSA-N
• INCHI: 1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1
• Isomeric SMILES: CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Aminosaccharides
          • Level6 Aminoglycosides

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Aminosaccharides
• Direct Parent: Aminoglycosides
• Alternative Parents: Macrolides and analogues Disaccharides O-glycosyl compounds Short-chain hydroxy acids and derivatives Beta hydroxy acids and derivatives Sugar acids and derivatives Oxanes Alpha hydroxy acids and derivatives Fatty acids and conjugates Dicarboxylic acids and derivatives Alpha-hydrogen aldehydes Tertiary alcohols Secondary alcohols 1,2-aminoalcohols Cyclic ketones Trialkylamines Lactones Amino acids and derivatives Carboxylic acid esters Oxacyclic compounds Acetals Dialkyl ethers Carboxylic acids Hydrocarbon derivatives Organopnictogen compounds Organic oxides
• Molecular Framework: Not available
• Substituents: Aminoglycoside core - Macrolide - Disaccharide - Glycosyl compound - O-glycosyl compound - Beta-hydroxy acid - Short-chain hydroxy acid - Sugar acid - Alpha-hydroxy acid - Dicarboxylic acid or derivatives - Hydroxy acid - Fatty acid - Oxane - Tertiary alcohol - Alpha-hydrogen aldehyde - Secondary alcohol - Tertiary aliphatic amine - Tertiary amine - Cyclic ketone - Lactone - Ketone - 1,2-aminoalcohol - Amino acid or derivatives - Carboxylic acid ester - Oxacycle - Organoheterocyclic compound - Ether - Carboxylic acid derivative - Carboxylic acid - Dialkyl ether - Acetal - Organic nitrogen compound - Aldehyde - Amine - Organopnictogen compound - Carbonyl group - Organic oxide - Organonitrogen compound - Alcohol - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as aminoglycosides. These are molecules or a portion of a molecule composed of amino-modified sugars.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 1066.200 g/mol
• Hydrogen Bond Donor Count: 9
• Hydrogen Bond Acceptor Count: 24
• Rotatable Bond Count: 16
• Exact Mass: 1065.54 Da
• Monoisotopic Mass: 1065.54 Da
• Topological Polar Surface Area: 354.000 Ų
• Heavy Atom Count: 74
• Formal Charge: 0
• Complexity: 1700.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 23
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 2
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 2
• Covalently-Bonded Unit Count: 2

XLogP3

References

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