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· · COA & SDS available for every product · Same-day shipping on in-stock items UBP 302 - Moligand™, ≥98%(HPLC) , Antagonist of GluK1, CAS No.745055-91-8, Antagonist of GluK1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
2-({3-[(2S)-2-amino-2-carboxyethyl]-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)benzoic acid | HMS3413E11 | UBP302 | UBP-302 | UBP302, >=98% (HPLC) | NCGC00025352-01 | SR-01000597533 | STK246312 | NCGC00329542-01 | DTXSID80423571 | UBP 302 | 2-Hydroxyp
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
2-({3-[(2S)-2-amino-2-carboxyethyl]-2, 6-dioxo-3, 6-dihydropyrimidin-1(2H)-yl}methyl)benzoic acid | HMS3413E11 | UBP302 | UBP-302 | UBP302, >=98% (HPLC) | NCGC00025352-01 | SR-01000597533 | STK246312 | NCGC00329542-01 | DTXSID80423571 | UBP 302 | 2-Hydroxyp
Specifications & Purity
Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent and selective GluK1 (formally GluR5)-subunit containing kainate receptor antagonist (apparent KD= 402 nM); active enantiomer of UBP 296. Displays ~ 260-fold selectivity over AMPA receptors, ~ 90-fold selectivity over recombinant human GluK2 (formal
Mechanism of action
Antagonist of GluK1
Names and Identifiers Canonical Smiles C1=CC=C(C(=C1)CN2C(=O)C=CN(C2=O)CC(C(=O)O)N)C(=O)O IUPAC Name 2-[[3-[(2S)-2-amino-2-carboxyethyl]-2,6-dioxopyrimidin-1-yl]methyl]benzoic acid InChIKey UUIYULWYHDSXHL-NSHDSACASA-N INCHI 1S/C15H15N3O6/c16-11(14(22)23)8-17-6-5-12(19)18(15(17)24)7-9-3-1-2-4-10(9)13(20)21/h1-6,11H,7-8,16H2,(H,20,21)(H,22,23)/t11-/m0/s1 Isomeric SMILES C1=CC=C(C(=C1)CN2C(=O)C=CN(C2=O)C[C@@H](C(=O)O)N)C(=O)O WGK Germany 3 PubChem CID 6420161 Molecular Weight 333.3
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic acids and derivatives Class Carboxylic acids and derivatives Subclass Amino acids, peptides, and analogues Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids Direct Parent L-alpha-amino acids Alternative Parents Benzoic acids Benzoyl derivatives Pyrimidones Hydropyrimidines Vinylogous amides Heteroaromatic compounds Ureas Amino acids Lactams Monocarboxylic acids and derivatives Azacyclic compounds Carboxylic acids Carbonyl compounds Hydrocarbon derivatives Monoalkylamines Organic oxides Molecular Framework Aromatic heteromonocyclic compounds Substituents L-alpha-amino acid - Benzoic acid or derivatives - Benzoic acid - Benzoyl - Pyrimidone - Monocyclic benzene moiety - Hydropyrimidine - Benzenoid - Pyrimidine - Heteroaromatic compound - Vinylogous amide - Amino acid - Lactam - Urea - Carboxylic acid - Azacycle - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Primary aliphatic amine - Organic nitrogen compound - Amine - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Primary amine - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:1eq. NaOH, Max Conc. mg/mL: 8.33, Max Conc. mM: 25; Solvent:DMSO, Max Conc. mg/mL: 6.67, Max Conc. mM: 20 with gentle warming Molecular Weight 333.300 g/mol XLogP3 -3.200 Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 6 Exact Mass 333.096 Da Monoisotopic Mass 333.096 Da Topological Polar Surface Area 141.000 Ų Heavy Atom Count 24 Formal Charge 0 Complexity 576.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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