UCM 608 - ≥98%(HPLC) , CAS No.151889-03-1

CAS: 151889-03-1 Cat. No.: P288352 Molecular Weight: 308.38 PubChem CID: 4018512
AVAILABLE TO ORDER
GRADE & PURITY ≥98%(HPLC)
Synonyms
UCM608;UCM-608 | CHEBI:107661 | Q27185983 | UCM 608 | N-[2-(5-METHOXY-2-PHENYLINDOL-3-YL)ETHYL]ACETAMIDE | AM20030035 | PDSP2_001778 | SR-01000597657 | NCGC00024727-02 | HMS3675O18 | PDSP1_001796 | HY-101074 | Tocris-0680 | BRD-K41869275-001-01-0 | Melato
Storage
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
P288352-5mg
2
$179.90
10mg
P288352-10mg
3
$287.90
25mg
P288352-25mg
2
$575.90
50mg
P288352-50mg
2
$935.90
100mg
P288352-100mg
2
$1,493.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Product Describtion:

UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4.

Specifications

Synonyms
UCM608;UCM-608 | CHEBI:107661 | Q27185983 | UCM 608 | N-[2-(5-METHOXY-2-PHENYLINDOL-3-YL)ETHYL]ACETAMIDE | AM20030035 | PDSP2_001778 | SR-01000597657 | NCGC00024727-02 | HMS3675O18 | PDSP1_001796 | HY-101074 | Tocris-0680 | BRD-K41869275-001-01-0 | Melato
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Highly potent melatonin agonist; displays higher affinity and greater potency than melatonin itself. The EC50values for G protein activation in MT1and MT2-transfected cells are 65 and 58 pM respectively.
Storage
Store at -20°C, Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%(HPLC)
Names and Identifiers
Pubchem Sid488194651
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488194651
Canonical SmilesCC(=O)NCCC1=C(NC2=C1C=C(C=C2)OC)C3=CC=CC=C3
IUPAC NameN-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide
InChIKeyOFCLARYYBGKCHN-UHFFFAOYSA-N
INCHI1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22)
Isomeric SMILES CC(=O)NCCC1=C(NC2=C1C=C(C=C2)OC)C3=CC=CC=C3
PubChem CID 4018512
Molecular Weight 308.38

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassIndoles and derivatives
SubclassIndoles
Intermediate Tree Nodes Not available
Direct Parent2-phenylindoles
Alternative Parents Phenylpyrroles  N-acetyl-2-arylethylamines  3-alkylindoles  Anisoles  Alkyl aryl ethers  Benzene and substituted derivatives  Heteroaromatic compounds  Secondary carboxylic acid amides  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents 2-phenylindole - 2-phenylpyrrole - N-acetyl-2-arylethylamine - 3-alkylindole - Anisole - Alkyl aryl ether - Monocyclic benzene moiety - Substituted pyrrole - Benzenoid - Pyrrole - Heteroaromatic compound - Acetamide - Secondary carboxylic acid amide - Carboxamide group - Ether - Carboxylic acid derivative - Azacycle - Hydrocarbon derivative - Organic nitrogen compound - Organic oxide - Organooxygen compound - Organonitrogen compound - Carbonyl group - Organopnictogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as 2-phenylindoles. These are indoles substituted at the 2-position with a phenyl group.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
MTNR1A Tclin Melatonin receptor 1A (2519 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MTNR1A Tclin Melatonin receptor (989 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Melatonin receptor 1B (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cruzipain (33337 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Impa1 Inositol monophosphatase 1 (16203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
D2311688Certificate of AnalysisJan 20, 2026 P288352
D2311696Certificate of AnalysisJan 20, 2026 P288352
D2311697Certificate of AnalysisJan 20, 2026 P288352
D2311699Certificate of AnalysisJan 20, 2026 P288352
D2311707Certificate of AnalysisJan 20, 2026 P288352
D2311710Certificate of AnalysisJan 20, 2026 P288352
D2311711Certificate of AnalysisJan 20, 2026 P288352
D2311726Certificate of AnalysisJan 20, 2026 P288352
D2311735Certificate of AnalysisJan 20, 2026 P288352
D2311736Certificate of AnalysisJan 20, 2026 P288352
Chemical and Physical Properties
SolubilitySolvent:ethanol, Max Conc. mg/mL: 30.84, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 30.84, Max Conc. mM: 100
Molecular Weight308.400 g/mol
XLogP33.300
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Exact Mass308.152 Da
Monoisotopic Mass308.152 Da
Topological Polar Surface Area54.100 Ų
Heavy Atom Count23
Formal Charge0
Complexity395.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.