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USP7-IN-7 , CAS No.2413944-70-2
AVAILABLE TO ORDER
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
USP7-IN-7 (compound 124) is a USP7 inhibitor with an IC 50 value ＜10 nM. USP7-IN-7 shows cytotoxicity against p53-mutant cancer cell lines, p53 wild-type blood cancer and neuroblastoma cell lines with low nanomolar values. USP7-IN-7 can be used for cancer research.
In Vitro
USP7-IN-7 (0-1 μM) shows cytotoxicity against p53 wild-type blood cancer cell lines with CC 50 values of 0.2, 0.2, 0.4 and 0.1 μM for M07e, OCI-AML5, MOLM13 and MM.IS, respectively. USP7-IN-7 (0-2 μM) shows cytotoxicity against p53 wild-type neuroblastoma cell lines with CC 50 values of 1.9, 0.6 and 0.5 μM for SH-SY5Y, CHP-134 and NB-1, respectively. USP7-IN-7 (0-25 μM) shows cytotoxicity against p53-mutant cancer cell lines with CC 50 values of 0.5, 0.2 and 0.2 μM for H526, LA-N-2 and SK-N-DZ, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Specifications
Biochemical and Physiological Mechanisms
USP7-IN-7 (compound 124) is a USP7 inhibitor with an IC 50 value ＜10 nM. USP7-IN-7 shows cytotoxicity against p53-mutant cancer cell lines, p53 wild-type blood cancer and neuroblastoma cell lines with low nanomolar values. USP7-IN-7 can be used for cancer
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
| Canonical Smiles | O=C(N1CC2=CC3=NC=CC(C4=CC(Cl)=CC(C)=C4C[C@@H]5CNCCO5)=C3S2)C6C(C)(C)C6C1=O |
|---|---|
| Molecular Weight | 510.05 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
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