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· · COA & SDS available for every product · Same-day shipping on in-stock items W146 - Moligand™, ≥98%(HPLC) , Antagonist of S1P 1 receptor, CAS No.909725-61-7, Antagonist of S1P 1 receptor
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
ML056 | W 146 | ML5 | HY-101395 | {(3r)-3-Amino-4-[(3-Hexylphenyl)amino]-4-Oxobutyl}phosphonic Acid | DTXSID50425901 | BDBM50324676 | [(3R)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid | GTPL2931 | ML056 | (R)-(3-Amino-4-((3-hexylphenyl)amino)-4-
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Product description：
W146 hydrate functions as an orthosteric antagonist. It is associated with blood lymphopenia and lung edema in mice.
Application：
W146 hydrate has been used to assess vascular permeability in mice.
Specifications Synonyms
ML056 | W 146 | ML5 | HY-101395 | {(3r)-3-Amino-4-[(3-Hexylphenyl)amino]-4-Oxobutyl}phosphonic Acid | DTXSID50425901 | BDBM50324676 | [(3R)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid | GTPL2931 | ML056 | (R)-(3-Amino-4-((3-hexylphenyl)amino)-4-
Specifications & Purity
Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent sphingosine-1-phosphate receptor S1P1selective antagonist (Ki= 18 nM); displays no effect at S1P2, S1P3or S1P5. Enhances capillary leakage and restores lymphocyte egressin vivo.Potent S1P(1) competitive antagonist; Ki = 10-77 nM.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Antagonist of S1P 1 receptor
Names and Identifiers Canonical Smiles CCCCCCC1=CC(=CC=C1)NC(=O)C(CCP(=O)(O)O)N IUPAC Name [(3R)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid InChIKey FWJRVGZWNDOOFH-OAHLLOKOSA-N INCHI 1S/C16H27N2O4P/c1-2-3-4-5-7-13-8-6-9-14(12-13)18-16(19)15(17)10-11-23(20,21)22/h6,8-9,12,15H,2-5,7,10-11,17H2,1H3,(H,18,19)(H2,20,21,22)/t15-/m1/s1 Isomeric SMILES CCCCCCC1=CC(=CC=C1)NC(=O)[C@@H](CCP(=O)(O)O)N PubChem CID 6857802 Molecular Weight 342.37
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic acids and derivatives Class Carboxylic acids and derivatives Subclass Amino acids, peptides, and analogues Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives Direct Parent Alpha amino acid amides Alternative Parents Anilides N-arylamides Fatty amides Organic phosphonic acids Secondary carboxylic acid amides Organophosphorus compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds Molecular Framework Aromatic homomonocyclic compounds Substituents Alpha-amino acid amide - Anilide - N-arylamide - Monocyclic benzene moiety - Fatty amide - Fatty acyl - Benzenoid - Organophosphonic acid - Organophosphonic acid derivative - Carboxamide group - Secondary carboxylic acid amide - Organooxygen compound - Organonitrogen compound - Amine - Hydrocarbon derivative - Primary aliphatic amine - Organic oxide - Organic nitrogen compound - Carbonyl group - Organic oxygen compound - Organophosphorus compound - Primary amine - Aromatic homomonocyclic compound Description This compound belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:3eq. NaOH, Max Conc. mg/mL: 6.85, Max Conc. mM: 20 Molecular Weight 342.370 g/mol XLogP3 -0.600 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 10 Exact Mass 342.171 Da Monoisotopic Mass 342.171 Da Topological Polar Surface Area 113.000 Ų Heavy Atom Count 23 Formal Charge 0 Complexity 400.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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