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· · COA & SDS available for every product · Same-day shipping on in-stock items Y-27632 - Moligand™, 10mM in DMSO , CAS No.146986-50-7
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
BDBM86729 | Bio2_000937 | NCGC00092276-06 | HY-10071 | Y27632 | y-27632 | 4-[(1R)-1-aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide | HMS1792N15 | HMS3403N15 | trans-4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexanecarboxamide | CCG-204428 | NCGC00092276-10
Shipped In
Dry ice packs + Cold packs
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Why this grade Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
BDBM86729 | Bio2_000937 | NCGC00092276-06 | HY-10071 | Y27632 | y-27632 | 4-[(1R)-1-aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide | HMS1792N15 | HMS3403N15 | trans-4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexanecarboxamide | CCG-204428 | NCGC00092276-10
Specifications & Purity
Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms
Y-27632 is ROCK inhibitor, as a novel bronchodilator. Y-27632 is available with IC50 of 3.3±0.25 μM and 2.8±0.2 μM in human and rabbit tissues, respectively.
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Canonical Smiles CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N IUPAC Name 4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide InChIKey IYOZTVGMEWJPKR-VOMCLLRMSA-N INCHI 1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11?,12?/m1/s1 Isomeric SMILES C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N PubChem CID 448042 Molecular Weight 247.34
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic nitrogen compounds Class Organonitrogen compounds Subclass N-arylamides Intermediate Tree Nodes Not available Direct Parent N-arylamides Alternative Parents Pyridines and derivatives Heteroaromatic compounds Secondary carboxylic acid amides Amino acids and derivatives Azacyclic compounds Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds Molecular Framework Aromatic heteromonocyclic compounds Substituents N-arylamide - Pyridine - Heteroaromatic compound - Amino acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Organoheterocyclic compound - Carboxylic acid derivative - Azacycle - Organopnictogen compound - Organic oxygen compound - Primary amine - Organooxygen compound - Primary aliphatic amine - Amine - Carbonyl group - Organic oxide - Hydrocarbon derivative - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as n-arylamides. These are organic compounds that contain a carboxamide group that is N-linked to a aryl group. They have the generic structure RC(=O)N(R')H, R = organyl group and R'= aryl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 247.340 g/mol XLogP3 0.900 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 3 Exact Mass 247.168 Da Monoisotopic Mass 247.168 Da Topological Polar Surface Area 68.000 Ų Heavy Atom Count 18 Formal Charge 0 Complexity 268.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Documents & Articles Citations of This Product References 1. Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang. (2025) ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 57 (1): (14). [PMID:41201025 ] [10.3892/ijmm.2025.5685 ]
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