Zeoh , CAS No.Z1452913

CAS: Z1452913 Cat. No.: Z1452913 Formula: C₂₅H₃₅NO₇ Molecular Weight: 461.55

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Zeoh, an immunizing and heterologous hapten, contains one unprotected OH group at a distal position.

Specifications

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

Molecular Weight

461.55

Application Protocols

No application protocols have been provided for Zeoh.

• Item-specific tested applications, recommended dilutions, or positive controls: Not specified for this item; refer to CoA/Spec Sheet.

• General protocol guidance (not item-specific):

  • Prepare small test aliquots to optimize concentration and incubation times.
  • Validate with positive/negative controls appropriate to the assay type (e.g., known binder, vehicle control).
  • Document lot number, solvent, buffer composition, and temperature for reproducibility.

• Support:

  • Contact technical support with your intended application to obtain any available internal guidance aligned with the specific lot.

Biological Roles

No biological function or mechanistic role can be described for Zeoh without an established structure or class.

• Item-specific biological information: Not specified for this item; refer to CoA/Spec Sheet.

• General guidance (not item-specific):

  • For bioreagents used in life sciences, confirm whether the material is a protein/peptide, nucleic acid, small-molecule probe, or polysaccharide, as handling and stability differ substantially.
  • If used in cell-based assays, verify endotoxin levels, sterility, and vehicle toxicity prior to biological exposure.
  • For enzymatic or binding assays, establish Km/IC50/EC50 only after identity is confirmed and validated reference standards are available.

• Documentation:

  • Record detailed experimental context (cell line, medium, passage, incubation time, temperature) to interpret any observed biological effects reproducibly.

Research use only: No clinical or diagnostic claims are made for this product.

Buffer Applications

Buffer system guidance is not applicable without knowing the molecule’s acid–base properties and stability profile.

• Item-specific buffering data: Not specified for this item; refer to CoA/Spec Sheet.

• General notes (not item-specific):

  • If Zeoh requires dissolution in aqueous media, start with neutral buffers such as PBS (pH ~7.2–7.4) or HEPES (pH 7.2–7.6) and adjust only if stability permits.
  • Avoid buffers containing primary amines (e.g., Tris) if the reagent is used in amine-reactive labeling chemistry.
  • Maintain ionic strength consistent with downstream assays to prevent precipitation or aggregation.

• Practical tip:

  • Conduct a small pH and ionic strength screen to identify optimal buffer conditions once the CoA clarifies chemical class and compatibility.

Green Alternatives

Without a defined chemical identity or solvent system, specific greener substitutions cannot be prescribed for this item.

• General principles (not item-specific):

  • Prefer aqueous buffers over high-VOC organic solvents when solubility and stability permit.
  • When organic solvation is necessary, consider bio-based or lower-toxicity solvents (e.g., ethanol, ethyl acetate, propylene carbonate) and minimize DMSO/DMF volumes where feasible.
  • Optimize atom economy and reduce auxiliaries (salts, protecting groups) in any associated synthesis or derivatization.
  • Implement microscale protocols to reduce waste, and utilize closed systems to minimize exposure and emissions.

• Process considerations:

  • Evaluate solvent recovery and cold-chain efficiency (consolidated shipments, insulated packaging reuse) to reduce environmental impact.

• Recommendation:

  • Once the identity and use-case are established from the CoA, conduct a Green Chemistry Solvent Selection Guide review tailored to the exact workflow.

Pharmaceutical Uses

No pharmacopeial status or excipient role is provided for this product.

• Item-specific pharmaceutical information: Not specified for this item; refer to CoA/Spec Sheet.

• General, non-clinical guidance (not item-specific):

  • For pre-formulation screening, characterize solubility, pH stability, and photostability in common vehicles (water, saline, buffered systems) if the reagent is evaluated as a tool compound.
  • Document residual solvents, impurities, and endotoxin if materials are used in upstream research relevant to formulation science (not for human use).

• Compliance note:

  • This product is labeled For research use only and is not intended for diagnostic, therapeutic, or clinical applications.

Physical Properties

No item-specific physicochemical data were provided.

• Item-specific values:

  • Appearance: Not specified for this item; refer to CoA/Spec Sheet.
  • Melting/Freezing Point: Not specified for this item; refer to CoA/Spec Sheet.
  • Boiling Point: Not specified for this item; refer to CoA/Spec Sheet.
  • Density: Not specified for this item; refer to CoA/Spec Sheet.
  • Solubility: Not specified for this item; refer to CoA/Spec Sheet.
  • pKa/logP/refractive index: Not specified for this item; refer to CoA/Spec Sheet.

• Practical guidance (general, not item-specific):

  • If Zeoh is supplied as a solid bioreagent (common in life science categories), typical solvents/buffers include water, PBS, or tris-based buffers; ensure compatibility per the CoA.
  • If supplied as a solution, verify the vehicle, concentration, and stabilizers (e.g., glycerol, salts) before dilution or freezing.
  • For hygroscopic or air-sensitive materials, minimize atmospheric exposure (desiccator, inert gas) and record mass quickly.

• Verification:

  • Always confirm lot-specific details (appearance, solubility limits, concentration) on the Certificate of Analysis prior to use.

Quality & Grades

Item-specific quality designations were not provided.

• Grade/Purity for this item: Not specified for this item; refer to CoA/Spec Sheet.

• What to look for on the CoA (general guidance):

  • Assay/Purity method (HPLC, LC–MS, GC, SDS-PAGE, UV/Vis) and acceptance criteria.
  • Identity confirmation (NMR, MS, sequencing for biomolecules, or peptide content if applicable).
  • Residuals/contaminants relevant to life science use (endotoxin, bioburden, DNase/RNase, protease, heavy metals where relevant).
  • Functional tests (activity, binding, or performance in specified assays) when applicable to the material type.
  • Stabilizers/Excipients (e.g., salts, glycerol, preservatives) that impact storage and downstream applications.

• Implications for method development (general):

  • For analytical workflows, absence of a defined UV cutoff or fluorophore content necessitates preliminary baseline scans to set detection wavelengths.
  • For bioassays or omics workflows, confirm endotoxin and nuclease specifications to avoid confounding results.

• Recommendation:

  • Request the lot-specific CoA/Spec Sheet prior to critical experiments to verify grade suitability (e.g., molecular biology grade, cell culture compatible, analytical grade).

Reaction & Applications

Because the chemical identity and functional groups of Zeoh are not disclosed, specific reaction classes or named transformations cannot be assigned.

• Item-specific application notes: Not provided in the catalog entry; refer to CoA/Spec Sheet.

• General life science application contexts (not item-specific):

  • If Zeoh is a biochemical reagent, typical uses may include assay development, labeling, binding studies, or standards. Confirm compatible assay conditions (pH, ionic strength, temperature) from the CoA.
  • For small-molecule tools, common workflows include stock preparation in DMSO, serial dilution, and exposure to biological systems; pre-validate solubility and stability.

• Practical tips (generic):

  • Verify stability to light/temperature; protect from light if chromophores/fluorophores are suspected.
  • Establish a stability-indicating method (e.g., LC–MS or HPLC-UV) for time-course monitoring in your matrix of interest.
  • Run pilot scale tests to optimize concentration ranges and minimize nonspecific effects or solvent artifacts.

• Documentation:

  • Record lot number, preparation details, and instrument methods to enable traceable reproducibility.

Reaction Conditions

There are no item-specific reaction conditions available for Zeoh.

• Item-specific parameters (solvent, temperature, catalysts, time): Not specified for this item; refer to CoA/Spec Sheet.

• General advice (not item-specific):

  • For small molecules: start with ambient conditions, inert atmosphere only if the structure suggests air/moisture sensitivity; titrate temperature based on stability monitoring (TLC/HPLC/LC–MS).
  • For biomolecular conjugations: maintain near-neutral pH 6.5–7.5, moderate ionic strength, and control stoichiometry; protect from light if chromophores are present.
  • Establish stability-indicating analytics before scaling (e.g., HPLC-UV or LC–MS).

• Expected yields and kinetics: Will depend entirely on the specific chemistry; consult literature once identity is confirmed.

Safety & Handling

Safety overview for research use only materials.

• Item-specific hazard data:

  • GHS Classification: Not specified for this item; refer to SDS.
  • Signal Word / H-Statements / Pictograms: Not specified for this item; refer to SDS.

• Storage and transport (from Product Data):

  • Storage: Store at −20°C.
  • Shipping: Ice chest + ice pads (cold-chain shipment on arrival).

• General laboratory precautions (not item-specific):

  • Wear appropriate PPE: lab coat, safety glasses, and chemically resistant gloves.
  • Handle powders/lyophilizates in a fume hood or biosafety cabinet as appropriate to reduce inhalation/contamination risks.
  • Avoid repeated freeze–thaw; aliquot upon first thaw if solution-based.
  • Prevent cross-contamination: use sterile tools and dedicated pipette tips if sterility is required.
  • Incompatibilities to consider (generic): strong oxidizers/reducers, extreme pH, and proteases/nucleases for biomolecules.

• First-aid overview (consult SDS for authoritative guidance):

  • Inhalation: move to fresh air; seek medical attention if symptoms persist.
  • Skin/eye contact: rinse with water for at least 15 minutes; remove contaminated clothing.
  • Ingestion: rinse mouth; do not induce vomiting; obtain medical advice.

• Waste disposal:

  • Dispose according to local regulations; treat as laboratory chemical waste. For bioactive agents, inactivate per institutional SOPs before disposal.

Solvent Selection

Solvent selection cannot be item-specific without solubility data.

• Item-specific solubility/miscibility: Not specified for this item; refer to CoA/Spec Sheet.

• General guidance for life science reagents (not item-specific):

  • Aqueous systems: Water, PBS, Tris, HEPES are common for proteins/peptides and many bioactive small molecules at physiological pH.
  • Organic co-solvents: DMSO, DMF, ethanol can aid dissolution of hydrophobic small molecules; keep final assay concentrations low (e.g., ≤0.1–1% v/v) to avoid biological interference.
  • pH control: Adjust pH only if the CoA indicates stability; avoid extreme pH that may induce hydrolysis or denaturation.

• Practical tips:

  • Begin with a small-scale solubility screen (water, buffer, DMSO, ethanol) at ambient temperature.
  • Filter through 0.22 µm if sterility/clarity are required and the material is filter-stable.
  • Document the exact solvent lot and composition for reproducibility.

• When to choose alternatives:

  • If precipitation occurs on dilution from DMSO into aqueous media, pre-formulate with co-solvent or cyclodextrin systems (if compatible), or adjust dilution order slowly with vortexing.

Storage & Reconstitution

Cold-chain and storage guidance based on provided data.

• Item-specific storage and shipping (from Product Data):

  • Storage: Store at −20°C.
  • Shipped: Ice chest + ice pads (maintain cold chain upon receipt).

• Reconstitution and handling (general, not item-specific):

  • If supplied as a solid or lyophilizate: reconstitute with a suitable solvent or buffer only after confirming compatibility on the CoA. Use sterile, nuclease-free water/buffer if sterility is required.
  • If supplied as a solution: keep on ice during handling; mix gently; avoid vortexing if the material is a protein or nanoparticle.
  • Prepare single-use aliquots to prevent repeated freeze–thaw cycles; store aliquots at −20°C or per CoA guidance. For sensitive biomolecules, consider −80°C storage if permitted.
  • Protect from light and moisture when applicable; use amber vials or foil wrap if chromophores are suspected.

• Stability notes:

  • Thaw on ice or at 2–8°C; record thaw dates. Discard aliquots showing precipitation, turbidity, or off-odors unless expected for the material.

• Documentation:

  • Retain CoA/Spec Sheet and SDS with the received lot, and note storage conditions and any deviations for QA/QC traceability.

Structure & Identity

Concise identity summary for professional users.

• Item-specific facts (from Product Data):

  • Product Name: Zeoh (SKU: Z1452913)
  • CAS: Z1452913 (catalog placeholder; not a registry CAS)
  • Molecular Formula: Not specified for this item; refer to CoA/Spec Sheet.
  • Molecular Weight: Not specified for this item; refer to CoA/Spec Sheet.
  • InChIKey: Not specified for this item; refer to CoA/Spec Sheet.
  • SMILES: Not specified for this item; refer to CoA/Spec Sheet.

• Structural features and 2D description:

  • Not available. No structural identifiers (SMILES/InChI) were provided, so ring systems, functional groups, and stereochemistry cannot be detailed for this item.

• Notes on identifiers (general guidance):

  • If you require structure-based planning (e.g., buffer compatibility, spectroscopy, or derivatization), request the latest CoA/Specification Sheet for full identifiers.
  • For cheminformatics workflows, confirm the definitive CAS RN and structure prior to procurement; the listed CAS here appears to be an internal catalog code rather than a registry number.

Synthetic Utility

Synthetic utility cannot be defined without structural information.

• Item-specific synthetic role: Not specified for this item; refer to CoA/Spec Sheet.

• General considerations (not item-specific):

  • If Zeoh is a small molecule building block, evaluate functional group compatibility, protecting group strategies, and coupling conditions based on the revealed structure.
  • For bioconjugation workflows, confirm presence of reactive handles (e.g., NHS esters, maleimides, azides/alkynes) and select orthogonal conjugation chemistries accordingly (e.g., click reactions, thiol–maleimide coupling).

• Recommendation:

  • Obtain full structure and purity data before integrating into synthetic sequences or conjugation protocols.

Target Specificity

Target or binding specificity cannot be described for this product without structural/class information.

• Item-specific target data, antigen/epitope, clone/isotype (if antibody), and species reactivity: Not specified for this item; refer to CoA/Spec Sheet.

• Guidance (not item-specific):

  • If Zeoh is an antibody or affinity reagent, request datasheets listing epitope mapping, host species, isotype, and validated applications.
  • If Zeoh is a small-molecule probe, seek target panel data (e.g., enzyme/subtype selectivity) and orthogonal confirmation assays.