Zimlovisertib - Moligand™, 10 mM in DMSO , CAS No.1817626-54-2

CAS: 1817626-54-2 Cat. No.: Z1498941 Molecular Weight: 361.37 EC Number: 815-268-1 PubChem CID: 118414016

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Zimlovisertib (PF-06650833) is a potent, selective and orally active inhibitor of interleukin-1 receptor associated kinase 4 ( IRAK4 ) with IC 50 s of 0.2 and 2.4 nM in the cell and PBMC assay, respectively. Zimlovisertib is used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Product Properties

• ALogP: 2

Names and Identifiers

• Isomeric SMILES: CC[C@H]1[C@H](NC(=O)[C@H]1F)COC2=NC=CC3=CC(=C(C=C32)OC)C(=O)N
• Alternate CAS: 1817626-54-2
• PubChem CID: 118414016
• MeSH Entry Terms: 1-(((2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide;PF-06650833
• Molecular Weight: 361.37