Abituzumab (anti-ITGAV) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to ITGAV, >95%, Human IgG2, INHIBITOR of Integrin alpha-V/beta-1 inhibitor, INHIBITOR of Integrin alpha-V/beta-1 inhibitor

CAS: 1105038-73-0 Cat. No.: Ab170472
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Human
Isotype
Human IgG2
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab170472-100μg
10
79,90US$
1mg
Ab170472-1mg
5
395,90US$
5mg
Ab170472-5mg
1
1.187,90US$
10mg
Ab170472-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
1.957,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Abituzumab (anti-ITGAV) is a recombinant monoclonal antibody to ITGAV. Abituzumab effectively reduces the phosphorylation of FAK, Akt and ERK. Abituzumab can be used in cancer research, particularly in prostate cancer.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name
Abituzumab (anti-ITGAV) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to ITGAV, >95%, Human IgG2, INHIBITOR of Integrin alpha-V/beta-1 inhibitor
Sinónimos
Abituzumab | antigen identified by monoclonal antibody L230 antibody | CD 51 antibody | CD51 antibody | DKFZp686A08142 antibody | Integrin alpha five antibody | integrin alpha V beta 3 antibody | Integrin alpha-5 antibody | integrin alpha-V antibody | Int
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Especies hospedadoras
Human
Especificidad
ITGAV
Aplicación
ELISA, Functional Assay, Flow cytometry, Kinetics (BLI), Kinetics (SPR)
Conjugación
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo de acción
INHIBITOR
Mecanismo de acción
INHIBITOR of Integrin alpha-V/beta-1 inhibitor
Tipo de anticuerpo
Primary antibody
Clonalidad
Recombinant
Isotipo
Human IgG2
Tipo de cadena ligera
kappa
SDS-PAGE
27.2 kDa (Light Chain) & 52.6 kDa (Heavy Chain), under reducing conditions; 175.0 kDa, under non-reducing conditions.
Método de purificación
Protein A purified
Pureza
>95%
Fuente
CHO supernatant
Concentración
See COA
CAS
1105038-73-0
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Abituzumab (anti-ITGAV) (Ab170472) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling ITGAV (red) with Abituzumab (anti-ITGAV) (Ab170472). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Abituzumab (anti-ITGAV) (Ab170472) - SEC
The purity of Abituzumab (anti-ITGAV) (Ab170472) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
ITGAV Tchem Integrin alpha-V (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGAV Tchem Vitronectin receptor alpha (65 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGAV Tchem Integrin alpha-V/beta-5 (589 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGAV Tchem Integrin alpha-V/beta-6 (509 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGAV Tchem Integrin alpha-V/beta-8 (181 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
ZJ26F0636268Certificate of AnalysisJun 09, 2026 Ab170472
ZJ23F0900973Certificate of AnalysisSep 06, 2023 Ab170472
ZJ23F0900974Certificate of AnalysisSep 06, 2023 Ab170472
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Xiuquan Jia, Jiping Ma, Min Wang, Zhongtian Du, Fang Lu, Feng Wang, Jie Xu.  (2014)  Promoted role of Cu(NO3)2 on aerobic oxidation of 5-hydroxymethylfurfural to 2,5-diformylfuran over VOSO4.  APPLIED CATALYSIS A-GENERAL,      [PMID:] [10.1016/j.apcata.2014.05.031]
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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