Cadonilimab (anti-PD-1&CTLA4) - Primary antibody, specific to PDCD1&CTLA4, Human IgG1, INHIBITOR of Programmed cell death protein 1 inhibitor, INHIBITOR of Programmed cell death protein 1 inhibitor

CAS: 2394841-59-7 Cat. No.: Ab182868
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Human
Isotype
Human IgG1-LALA-GA
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab182868-100μg
5
359,90US$
1mg
Ab182868-1mg
2
1.799,90US$
5mg
Ab182868-5mg
1
4.499,90US$
10mg
Ab182868-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
7.199,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Cadonilimab (anti-PD-1&CTLA4) is a targeting PD1/CTLA4 IgG1 scaffold Fc-engineered humanized antibody. Cadonilimab (anti-PD-1&CTLA4) can be used for researching metastatic cervical cancer.

Specifications

Product Name
Cadonilimab (anti-PD-1&CTLA4) - Primary antibody, specific to PDCD1&CTLA4, Human IgG1, INHIBITOR of Programmed cell death protein 1 inhibitor
Sinónimos
CD279 antibody | CD279 antigen antibody | hPD 1 antibody | hPD l antibody | hPD-1 antibody | hSLE1 antibody | PD 1 antibody | PD-1 antibody | PD1 antibody | PDCD 1 antibody | PDCD1 antibody | PDCD1_HUMAN antibody | Programmed cell death 1 antibody | Progr
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Mecanismos bioquímicos y fisiológicos
PD-1: Possible cell death inducer, in association with other factors. CTLA4: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger tha
Especies hospedadoras
Human
Especificidad
PDCD1&CTLA4
Conjugación
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo de acción
INHIBITOR
Mecanismo de acción
INHIBITOR of Programmed cell death protein 1 inhibitor
Isotipo
Human IgG1
Tipo de cadena ligera
kappa
Método de purificación
Protein A purified
Concentración
See COA
CAS
2394841-59-7
Almacenamiento y envío
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Cadonilimab (anti-PD-1&CTLA4) (Ab182868) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) Jurkat cells labelling PD-1&CTLA4 (red) with Cadonilimab (anti-PD-1&CTLA4) (Ab182868) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Cadonilimab (anti-PD-1&CTLA4) (Ab182868) - ELISA
Immobilized Recombinant Human PD-1 protein (rp176241) at 1.0 μg/mL can bind Cadonilimab (anti-PD-1&CTLA4) (Ab182868) with the EC50 of 90.80 ng/mL.

Cadonilimab (anti-PD-1&CTLA4) (Ab182868) - ELISA
Immobilized Recombinant Human CTLA-4 protein (rp176276) at 1.0 μg/mL can bind Cadonilimab (anti-PD-1&CTLA4) (Ab182868) with the EC₅₀ of 159.20 ng/mL.

Cadonilimab (anti-PD-1&CTLA4) (Ab182868) - SEC
The purity of Cadonilimab (anti-PD-1&CTLA4) (Ab182868) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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