Eculizumab (anti-Complement C5) - Primary antibody, specific to C5, >95%, Human IgG2+Human IgG4, INHIBITOR of Complement C5 inhibitor, INHIBITOR of Complement C5 inhibitor

CAS: 219685-50-4 Cat. No.: Ab170870
Disponible para pedir
CALIDAD & PUREZA Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Human, Mouse
Isotype
Human IgG2+Human IgG4
Conjugation
Unconjugated
★
Talla
USA
Alemania (EU)*
Precio
Cantidad
100μg
Ab170870-100μg
Fabricado bajo pedido en EE. UU. · 2–4 semanas ·
—
187,90US$
1mg
Ab170870-1mg
2 Disponible
—
748,90US$
5mg
Ab170870-5mg
1 Disponible
—
2.815,90US$
10mg
Ab170870-10mg
Fabricado bajo pedido en EE. UU. · 2–4 semanas ·
—
3.723,90US$
Enter a quantity for the sizes you want to add.
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Por qué esta calidad

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated para flujos de trabajo cromatográficos y analíticos sensibles que requieren una interferencia mínima de la línea base.

🌡

Almacenamiento y envío

Store at -80°C,Avoid repeated freezing and thawing Envío Dry ice packs + Cold packs. Consulte el COA específico del lote para conocer las especificaciones exactas.

📋

Documentos de calidad

SDS, COA, ficha técnica y hoja de especificaciones disponibles para descargar. COA específico del lote accesible mediante búsqueda por número de lote.

📚

Prueba documental

Citado en 0 publicaciones revisadas por pares sobre cromatografía, síntesis orgánica y reacciones de acoplamiento cruzado.

Descripción general

Eculizumab (anti-Complement C5) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab (anti-Complement C5) inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab (anti-Complement C5) has the potential for haemolysis research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Especificaciones

Product Name
Eculizumab (anti-Complement C5) - Primary antibody, specific to C5, >95%, Human IgG2+Human IgG4, INHIBITOR of Complement C5 inhibitor
Sinónimos
Anaphylatoxin C5a analog antibody | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 antibody | C5 antibody | C5a anaphylatoxin antibody | C5a antibody | C5b antibody | CO5_HUMAN antibody | Complement C5 alpha'' chain antibody | Complemen
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Especies hospedadoras
Human
Especificidad
C5
Conjugación
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo de acción
INHIBITOR
Mecanismo de acción
INHIBITOR of Complement C5 inhibitor
Isotipo
Human IgG2+Human IgG4
Tipo de cadena ligera
kappa
SDS-PAGE
26.1 kDa (Light Chain) & 51.6 kDa (Heavy Chain), under reducing conditions; 165.6 kDa, under non-reducing conditions.
Método de purificación
Protein A purified
Pureza
>95%
Concentración
See COA
CAS
219685-50-4
Product Line
Productos biológicos
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Eculizumab (anti-Complement C5) (Ab170870) - SEC
The purity of Eculizumab (anti-Complement C5) (Ab170870) is more than 95% verified by HPLC.

Documentación

📋 Hoja de datos de seguridad (SDS)

Documento completo sobre peligros, manipulación, almacenamiento y cumplimiento normativo.

<<<<<<< HEAD Descargar SDS → ======= Descargar SDS → >>>>>>> release248-p3

✅ Certificado de análisis (COA)

Datos de calidad específicos del lote. Introduzca su número de lote para obtener el COA exacto.

Buscar COA →

📊 Ficha técnica

Resumen de referencia rápida de las especificaciones y aplicaciones del producto.

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🔬 Hoja de especificaciones

Atributos de calidad completos y criterios de aceptación para esta calidad.

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Datos avanzados

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClaseCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Peptides
Direct ParentDipeptides
Alternative Parents Leucine and derivatives  N-carbamoyl-alpha amino acids and derivatives  N-acyl-alpha amino acids  Tryptamines and derivatives  Alpha amino acid amides  Indolecarboxylic acids  3-alkylindoles  Piperidinecarboxamides  Pyrrole carboxylic acids and derivatives  Medium-chain fatty acids  Amino fatty acids  Aralkylamines  Branched fatty acids  Heterocyclic fatty acids  Benzenoids  Substituted pyrroles  N-substituted carboxylic acid imides  N-acyl amines  Heteroaromatic compounds  Dicarboximides  Ureas  Amino acids  Carboxylic acids  Azacyclic compounds  Monocarboxylic acids and derivatives  Organic oxides  Organopnictogen compounds  Hydrocarbon derivatives  Carbonyl compounds  Monoalkylamines  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Alpha-dipeptide - Leucine or derivatives - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - N-carbamoyl-alpha-amino acid or derivatives - Alpha-amino acid amide - Indolecarboxylic acid - Indolecarboxylic acid derivative - Triptan - Alpha-amino acid or derivatives - 3-alkylindole - Indole - Indole or derivatives - 1-piperidinecarboxamide - Piperidinecarboxamide - Medium-chain fatty acid - Pyrrole-1-carboxylic acid or derivatives - Heterocyclic fatty acid - Branched fatty acid - Aralkylamine - Amino fatty acid - N-acyl-amine - Carboxylic acid imide, n-substituted - Fatty acyl - Fatty acid - Benzenoid - Piperidine - Substituted pyrrole - Dicarboximide - Carboxylic acid imide - Heteroaromatic compound - Pyrrole - Urea - Amino acid or derivatives - Carbonic acid derivative - Amino acid - Organoheterocyclic compound - Carboxylic acid - Azacycle - Monocarboxylic acid or derivatives - Organic oxygen compound - Organic nitrogen compound - Organic oxide - Organopnictogen compound - Organonitrogen compound - Organooxygen compound - Carbonyl group - Amine - Primary aliphatic amine - Hydrocarbon derivative - Primary amine - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
C5 Tclin Complement C5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeFechaArticulo
ZJ23F1001464ZJ23F1001464Certificate of AnalysisNov 01, 2023 Ab170870
ZJ23F1001463ZJ23F1001463Certificate of AnalysisNov 01, 2023 Ab170870
Preguntas frecuentes y artículos
Calculadoras de soluciones
Reseñas

Reseñas de cliente

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Ver la guía de calidades Animal Free → Ver la guía de calidades Carrier Free → Ver la guía de calidades Recombinant → Ver la guía de calidades Validated → Ver la guía de calidades ExactAb™ → Ver la guía de calidades Low Endotoxin → Ver la guía de calidades Azide Free →

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